Description

• DeneB 10mL with Lidocaine — Hyaluronic Acid Body Filler

  DeneB 10mL with Lidocaine is a hyaluronic acid (HA) body filler series from BioPlus Co., Ltd. in South Korea, the same manufacturer behind HyalDew. The series uses BioPlus’s MDM (Multi-Dimensional Matrix) and MCL (Multi-Level Crosslinking) technologies, building HA polymers in stages — from single molecules, to small micelles, to tight, cross-linked particles.

  Every syringe in this version includes 3mg/mL (0.3%) lidocaine, making the injection procedure nearly painless. DeneB comes in two variants, Classic-S and Classic-H, differing in viscosity and structural support.

  At a Glance

  HA Concentration	20mg/mL across both variants
  Lidocaine	3mg/mL (0.3%)
  Technology	MDM / MCL multi-stage crosslinking
  Duration	12–16 months
  Manufacturer	BioPlus Co., Ltd., South Korea

  Main Benefits

  • Built-in lidocaine: supports a nearly painless injection experience
  • Multi-stage crosslinking: MDM/MCL technology supports high cohesiveness and stable shape retention
  • Reduced BDDE residue: the multi-stage micro-bead process limits leftover crosslinking agent
  • High hydrophilicity: strong water-binding supports both volumizing and deep hydration
  • Low migration risk: the gel stays where it’s placed, supporting predictable, stable results

  Choosing the Right Variant

  Variant	Viscosity	Best For	Injection Depth
  DeneB Classic-S with Lidocaine	Medium (~49–52 N)	Deep moisturizing, flattening deep folds and wrinkles	Mid-to-deep dermis, subcutaneous
  DeneB Classic-H with Lidocaine	High	Buttock and breast augmentation, calf shaping, hip sculpting, body contouring	Deep subcutaneous

  What’s Inside

  Active Ingredient	Cross-linked Hyaluronic Acid — 20mg/mL
  Anesthetic	Lidocaine — 3mg/mL
  Technology	MDM / MCL multi-stage crosslinking
  Packing	1 × 10mL pre-filled syringe (without needle)
  Manufacturer	BioPlus Co., Ltd., South Korea

  How DeneB Works

  MDM/MCL technology builds HA polymers through sequential stages. Single HA molecules first link together, then associate into small micelles, and finally form tight, cross-linked particles. This staged approach supports both high viscosity and strong water-binding capacity, while limiting residual BDDE left over from the crosslinking process.

  The built-in lidocaine works independently of this structure. Once injected, it temporarily numbs the treatment area, which is part of why practitioners describe the procedure as almost painless. Because DeneB’s particles resist breaking down quickly, the gel also maintains its shape and position after injection rather than migrating into surrounding tissue.

  Who DeneB Suits

  Practitioners recommend DeneB with Lidocaine for patients interested in:

  • Non-surgical breast, buttock, or hip augmentation
  • Calf shape correction and body contouring
  • Deep hydration and flattening of deep folds or wrinkles
  • Patients who are more sensitive to injection discomfort

  Treatment Areas

  Breasts · Buttocks · Hips · Calves · Thighs · Abdomen

  Administration

  A licensed medical professional injects DeneB using different techniques depending on the treatment area and desired outcome. DeneB Classic-S typically suits mid-to-deep dermal or subcutaneous placement, while DeneB Classic-H is generally reserved for deeper subcutaneous placement where structural support matters most.

  Precautions

  • For use by licensed medical professionals only
  • Not for use in pregnancy or lactation
  • Avoid in patients with active infection at the injection site
  • Avoid in patients with known hypersensitivity to HA or lidocaine
  • Avoid in patients with coagulation disorders
  • Not for use in patients under 18

  Storage & Handling

  • Store at cool room temperature, between 2°C and 25°C
  • Single-use only — do not reuse or resterilize
  • For professional use only, by qualified and trained practitioners

  Frequently Asked Questions

  What is DeneB with Lidocaine?
  DeneB with Lidocaine is a hyaluronic acid body filler series from BioPlus, built on MDM/MCL crosslinking technology, with 3mg/mL lidocaine included for a more comfortable injection.

  How do I choose between Classic-S and Classic-H?
  DeneB Classic-S suits deep moisturizing and flattening deep folds. DeneB Classic-H suits structural applications like buttock or breast augmentation, where firmer support is needed.

  Is this version different from the standard DeneB 10mL?
  Yes. Both share the same HA concentration and MDM/MCL technology, but this version includes 3mg/mL lidocaine, while the standard version doesn’t.

  How long do results last?
  Results generally last 12 to 16 months, depending on the variant and treatment area.

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