PLLA Cube
Topical all-in-one skin booster with PLLA, PDRN, vitamin C, glutathione, sodium hyaluronate and plant-derived exosome · InCube™ technology · LabInCube, South Korea.
$103.90
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- PLLA Cube is a topical, all-in-one skin booster from LabInCube combining PLLA, PDRN, Vitamin C, Glutathione, and Sodium Hyaluronate with patented InCube™ delivery technology. It’s applied topically, often alongside microneedling or RF devices, rather than injected.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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PLLA Cube: a topical collagen skin booster with InCube™ technology
PLLA Cube is a topical, all-in-one skin booster from LabInCube in South Korea. Unlike injectable PLLA fillers, it is designed for topical professional use, and practitioners typically apply it with microneedling or radiofrequency (RF) devices to support delivery into the skin.
The formula combines six actives in one vial: poly-L-lactic acid (PLLA), PDRN, vitamin C (ethyl ascorbyl ether), glutathione, sodium hyaluronate and a plant-derived exosome extract. Everything arrives pre-formulated, so there is no mixing or layering of separate products. At the centre is InCube™, a patented encapsulation system built on metal-organic framework (MOF) science that is designed to protect delicate actives and release them evenly.
PLLA, PDRN, vitamin C, glutathione, sodium hyaluronate and plant-derived exosome.
MOF-based encapsulation designed to protect and release the actives evenly.
Pre-combined in one vial, with no mixing or layering.
Applied with microneedling or RF devices, not injected.
About PLLA Cube
Six actives are pre-combined in one vial, which can simplify a professional skin treatment.
Sodium hyaluronate gives hydration. Glutathione and vitamin C support an even-looking, brighter tone and protect against oxidative stress.
PDRN and the plant-derived exosome extract are described as supporting the skin’s own repair processes.
InCube™ is designed to keep fragile ingredients such as vitamin C and glutathione stable until the moment of use.
Skin concerns
Skin concerns where topical boosters of this type are used, as listed on our previous page.
Skin that looks dry, tired or lacks radiance.
Skin that has started to lose firmness.
Skin tone that looks uneven.
For patients who want a non-injectable option.
PLLA Cube is a professional skin product. How it is classified and what it may be used for are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training.
PLLA Cube specification
| Product type | Topical all-in-one skin booster |
| Poly-L-lactic acid (PLLA) | Supports collagen and skin elasticity |
| PDRN (sodium DNA) | Supports cell repair and skin vitality |
| Vitamin C (ethyl ascorbyl ether) | Antioxidant support |
| Glutathione | Supports an even-looking tone; antioxidant |
| Sodium hyaluronate | Hydration |
| Plant-derived exosome | Supports cell communication and skin recovery |
| Technology | InCube™ (MOF-based encapsulation and controlled release) |
| Manufacturer | LabInCube, South Korea |
| SKU | 06028 |
Before you order
- Topical product. PLLA Cube is applied to the skin, often with microneedling or RF. It is not an injectable. Confirm how it is classified and what you may use it for where you practise.
- Every vial ships in its original packaging with the lot number and expiry date.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
Priced per vial, with quantity discounts at five, ten and twenty vials.
What each component does
Poly-L-lactic acid (PLLA)
PLLA is a biodegradable polymer best known as an injectable collagen stimulator. In PLLA Cube it is used topically, and InCube™ helps keep the particles evenly dispersed and stable until application.
PDRN and plant-derived exosome
PDRN (sodium DNA) and the plant-derived exosome extract are described as supporting the skin’s own repair and recovery.
Vitamin C, glutathione and sodium hyaluronate
Vitamin C and glutathione are antioxidants. Sodium hyaluronate gives hydration. They are protected by InCube™ until use because they degrade quickly in air and light.
InCube™ technology
A patented encapsulation system built on metal-organic framework (MOF) science, designed for even release.
How PLLA Cube is used
Reference information for trained professionals. The manufacturer’s instructions and the instructions for the delivery device used take precedence over this page.
Step by step
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Assess and consent
Review skin condition, allergies, medication and scarring tendency. Explain that the product is topical and that results are gradual.
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Prepare the skin
Cleanse the skin and prepare it as for any professional treatment.
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Apply
Apply the product evenly across the treatment area.
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Optional delivery device
Use microneedling or an RF device if desired. These methods help the actives reach deeper than topical application alone.
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Aftercare
Follow standard aftercare for the delivery method used.
Administration notes
One vial, one application. Use each vial as a single application and discard any remainder.
- Use sterile technique with any device that breaks the skin surface, such as microneedling.
- Do not use on infected, inflamed or broken skin.
- Do not use in patients with known hypersensitivity to any ingredient.
After treatment
- Follow the aftercare for the device used
- Keep the skin clean and moisturised, and use daily SPF on treated areas
- Seek review for persistent redness, swelling, infection signs or a reaction
Storing and handling PLLA Cube
Store at room temperature, away from direct light.
Use before the expiry date, and only if the packaging and vial are intact.
Use each vial as a single application. Do not retain or reuse any remainder.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials and any needles or microneedling tips as clinical waste in line with local requirements.
What's included with PLLA Cube
Microneedling and RF devices are not supplied.
PLLA Cube — frequently asked questions
What is PLLA Cube?
A topical, all-in-one skin booster from LabInCube combining PLLA, PDRN, vitamin C, glutathione, sodium hyaluronate and a plant-derived exosome, using InCube™ technology.
Is PLLA Cube injected like a PLLA filler?
No. It is applied topically, often alongside microneedling or RF devices, and is not injected into the dermis.
What does InCube™ technology do?
It is a patented encapsulation system that helps keep the active ingredients stable and evenly distributed until the moment of application.
Is there a stronger version?
Yes. PLLA Cube Pink VOL has a higher PLLA content plus added PN.
Can it be used without a microneedling or RF device?
It can be applied topically on its own. Practitioners often pair it with microneedling or RF to help the actives reach deeper into the skin.
Who can buy and use this product?
We supply qualified aesthetic professionals and do not sell to consumers.
Customer Reviews
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The topical format was a big reason I considered this. I like having options beyond injectables.
The topical application format makes this quite different from the products we usually purchase.
I liked having a topical option to explore. Something different for a change.
Wanted something different from my usual order and this caught my attention. I’d happily get another box.
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