Proluma 200mg
Poly-D,L-lactide (PDLLA) collagen biostimulator · 200 mg per vial · amorphous 30–50 μm microspheres · Genèse Labs.
Original price was: $199.90.$159.90Current price is: $159.90.
- Proluma PDLLA is a CE-certified collagen biostimulator from Genèse Labs, formulated with poly-D,L-lactic acid for smooth, balanced facial correction. It suits early-stage volume loss in patients in their 30s–40s, with results lasting up to 18–24 months.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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Proluma 200mg: a PDLLA collagen biostimulator from Genèse Labs
Proluma PDLLA is an injectable collagen stimulator from Genèse Labs, formulated with poly-D,L-lactide (PDLLA) with carboxymethylcellulose (CMC) as a carrier component. Each vial contains 200 mg. Its microspheres measure 30 to 50 μm and are amorphous, with lower crystallinity. The product is listed as CE certified.
Unlike hyaluronic acid fillers, which add volume at the time of injection and fade as the HA is absorbed, a PDLLA product is used to prompt the body’s own collagen, so improvement is gradual. Proluma PDLLA is listed for smooth, balanced correction and early-stage volume loss, with typical areas of the cheeks, temples, nasolabial folds, neck and fine lines. It is for use by licensed professionals only.
Poly-D,L-lactide with CMC as a carrier component.
30 to 50 μm particles with lower crystallinity.
Priced per single vial. Boxes of 10 vials are available on request.
Listed as CE certified. Not FDA-approved as a finished product.
About Proluma 200mg
Used to prompt collagen over time, improving skin texture, elasticity and volume gradually.
Listed for smooth, balanced correction and early-stage volume loss.
The listing gives results appearing within 3 to 4 weeks and lasting up to 18 to 24 months. This varies by patient.
The amorphous, lower-crystallinity particles are described as dissolving smoothly, which makes it approachable for general practitioners as well as experienced injectors.
Treatment areas and indications
Areas and concerns where PDLLA collagen biostimulators are used, as listed on our previous page. Approved indications differ by market.
Early signs of ageing with mild volume loss.
Smooth, balanced volume correction.
Skin rejuvenation and touch-ups.
Skin quality of the neck.
Proluma PDLLA is an injectable medical product. Which indications are permitted and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training.
Proluma 200mg specification
| Product type | PDLLA collagen biostimulator |
| Active ingredient | Poly-D,L-lactide (PDLLA), with CMC as a carrier component |
| Dose per vial | 200 mg |
| Microspheres | 30 to 50 μm, amorphous, lower crystallinity |
| Cannula | 25G |
| Box size | 10 vials per box |
| Price basis | Per single vial |
| Duration (as listed) | Up to 18 to 24 months |
| Regulatory status | CE certified; not FDA-approved as a finished product |
| Manufacturer | Genèse Labs |
| SKU | 06001 |
Before you order
- Regulatory status. Proluma PDLLA is listed as CE certified. It is not FDA-approved as a finished product. Confirm the status in the country where you practise.
- Priced per single vial, not per box. Boxes of 10 vials are available. Contact us for bulk box pricing.
- Every vial ships in its original packaging with the lot number and expiry date.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
Quantity discounts apply at five, ten and twenty vials.
What each component does
Poly-D,L-lactide (PDLLA), 200 mg
PDLLA is a biodegradable polymer. Once injected, cells are described as migrating into the porous particles and laying down new collagen. Over time the polymer breaks down by hydrolysis into lactic acid, which the body metabolises into carbon dioxide and water, while the newly formed collagen takes its place.
CMC
Carboxymethylcellulose (CMC) helps keep the particles suspended.
FDA GRAS status of the material
PDLLA as a raw material is described as FDA GRAS (Generally Recognized As Safe). This refers to the material itself, not to FDA approval of the finished Proluma product.
Approved indications differ by country. Read the manufacturer’s instructions for use.
How it works
Once injected, cells are described as migrating into the porous PDLLA particles and laying down new collagen, which gradually replenishes volume. The PDLLA then breaks down by hydrolysis into lactic acid, which the body metabolises into carbon dioxide and water, while the newly formed collagen takes its place.
How Proluma PDLLA is used
Reference information for trained practitioners. The manufacturer’s instructions for use and your training take precedence over this page, including reconstitution volumes and hydration time, needle and cannula, plane and volume per site.
Step by step
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Assess and consent
Confirm the aim is gradual improvement, not immediate volume. Review medical history, autoimmune disease, scarring tendency, medication and previous fillers. Explain the risks, including nodules.
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Reconstitute
Reconstitute the lyophilised powder exactly as stated in the instructions for use, using aseptic technique, and allow the hydration time they give. Mix the suspension before drawing it up.
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Prepare the skin
Cleanse the skin thoroughly and remove make-up.
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Inject as taught
Use the plane, technique and cannula or needle stated in the instructions for use and your training. Keep the suspension agitated during treatment. Inject slowly with low pressure.
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Do not over-correct
A biostimulator is not a filler. Early swelling can look like a result and settles within days.
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Review
Assess the response over time and decide on any further treatment as a clinical decision.
Administration notes
Patients should not expect a permanent immediate result. Mild redness, swelling or bruising can occur straight after treatment. The collagen-based change develops over weeks.
- Single use. Do not reuse or resterilise. Discard any remainder.
- Do not inject into infected, inflamed or broken skin.
- Know how to recognise and manage nodules and vascular events.
- Dispose of needles and cannulas into a sharps container in line with local clinical waste rules.
After treatment
- Follow the post-treatment advice in the instructions for use and your clinic’s protocol
- An ice pack can reduce swelling or bruising; keep the ice from touching the skin directly
- Avoid sun and UV exposure until initial swelling and redness subside, and use sunscreen
- Seek urgent review for severe pain, blanching, skin colour change or a lump that grows or becomes tender
Storing and handling Proluma 200mg
Store as stated in the instructions for use, away from direct light.
Use before the expiry date, and only if the packaging and vial are intact.
Single patient, single session. Do not retain or reuse any remainder.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials, syringes and needles as clinical waste in line with local requirements.
What's included with Proluma 200mg
Reconstitution fluids, syringes, needles, cannulas and anaesthetic are not supplied.
Proluma 200mg — frequently asked questions
What is Proluma PDLLA?
A poly-D,L-lactide collagen biostimulator from Genèse Labs, 200 mg per vial, listed for smooth, balanced facial correction and early-stage volume loss.
How is Proluma PDLLA different from Proluma PLLA?
PDLLA has an amorphous, lower-crystallinity structure and is listed for earlier, smoother correction. PLLA is more crystalline and is listed for deeper, more structural volumising. Proluma 365mg is listed separately.
How long do the results last?
The listing gives results appearing within 3 to 4 weeks and lasting up to 18 to 24 months. It varies by patient and area.
Is the price per vial or per box?
Per single vial. Boxes of 10 vials are available, so contact us for bulk box pricing.
Is it FDA-approved?
No. Proluma PDLLA is listed as CE certified. PDLLA as a raw material is described as FDA GRAS, but that applies to the material, not to the finished product.
Who can buy and use this product?
Injectable products are for administration by licensed healthcare practitioners trained in injection technique. We supply qualified professionals and do not sell to consumers.
Customer Reviews
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I spent weeks researching before choosing this. Really pleased with my decision.
Exactly the kind of gradual improvement I prefer. Very happy with my decision.
A little patience goes a long way with this one. I'm happy with my decision.
Not the kind of product you judge after a few days. I'm pleased with my experience so far.
Subtle changes were exactly what I wanted. Very satisfied with my decision.
I appreciate products that don't look overdone. Really pleased with how everything turned out.
I almost forgot about it while waiting for the result, then suddenly realized how much had changed. Very happy I gave it time.
I knew this wasn't an instant-gratification product, so I gave it time. Very glad I did.
Definitely a slow burner, but I'm really happy I waited it out. Worth it.
Would 100% do this again. Just don't expect everything to happen overnight.
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