Poly-L-Lactic Acid ( PLLA )

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PLLA injections, representing a revolution in non-invasive aesthetic medicine, are becoming increasingly popular due to their biocompatibility and effectiveness in addressing various signs of aging and volume loss in the skin. They come from the family of injectable dermal fillers, which are making waves for offering a facelift-like effect without the need for surgery. Before we delve deeper, it’s crucial to understand the science behind the substances involved and the varying brands available in the market, including Proluma.

Ingredients and Composition

  1. Poly-L-Lactic Acid (PLLA): PLLA is a synthetic yet biodegradable polymer that forms the basis of these innovative injections. Its primary function is to stimulate collagen production, a vital protein in the skin responsible for its strength and structure. The primary ingredient, Poly-L-Lactic Acid, is a lab-made substance that is gradually absorbed by the body, promoting collagen synthesis over time. It has found multiple applications in the medical field, including being used in dissolvable stitches.
  2. Sterile Water: To prepare for injections, PLLA is mixed with sterile water to form a smooth solution that can be efficiently administered. This mixing is generally done a few hours before the injection to allow the particles to rehydrate fully.
  3. Lidocaine: In many cases, Lidocaine, a local anesthetic, is incorporated into the mixture to minimize any discomfort or pain that might occur during the procedure. This addition makes the procedure more tolerable for the patients.

Uses of PLLA Injections

  1. Facial Volume Restoration: PLLA injections are a go-to treatment for individuals seeking to restore lost volume in their faces, a common occurrence with aging. They efficiently fill in deep lines, wrinkles, and folds, offering a more youthful appearance. It’s a less invasive alternative to surgeries, offering significant results with minimal downtime.
  2. Collagen Stimulation: PLLA injections stand apart from other fillers because of their ability to stimulate the body to produce more collagen actively. This action helps to decrease the signs of aging gradually, fostering a natural and more youthful complexion over time.
  3. Buttock Augmentation: Apart from facial treatment, PLLA injections have found an off-label use in non-surgical buttock augmentation. This procedure aims to enhance the volume and shape of the buttocks, offering a fuller appearance. It’s imperative to note that this is an off-label use and must be conducted under the supervision of a skilled and experienced practitioner.

Proluma and Olidia – A Noteworthy Mention

Among the variety of brands offering PLLA injections, Proluma and Olidia distinctive are their composition. Proluma and Olidia are dermal fillers that primarily focuses on addressing facial wrinkles and folds. What makes Proluma and Olidia distinctive are their composition. It incorporates Poly-L-Lactic Acid along with Polycaprolactone (PCL) and a carrier gel that helps in easy application. This combination not only aids in immediate volume restoration but also stimulates collagen production over time, promising a sustained and natural-looking result. Moreover, Proluma has been noted to offer a good safety profile, with adverse effects being mostly injection-site related and temporary. Its role in modern aesthetic practices is steadily increasing, presenting an effective solution for those seeking a non-surgical approach to facial rejuvenation.

When to Opt for PLLA Injections

  1. Aging Skin: As individuals age, the skin begins to lose its firmness and volume, giving rise to lines, wrinkles, and sagging. PLLA injections offer a viable solution, allowing individuals to restore a youthful complexion without undergoing invasive surgeries.
  2. Following Significant Weight Loss: Individuals who have undergone substantial weight loss might experience a pronounced loss of facial volume. PLLA injections can serve as a remedy to restore facial volume and improve skin texture.
  3. Cosmetic Enhancements: PLLA injections have also found a place in cosmetic enhancements, catering to individuals looking to enhance their features subtly, even without significant signs of aging or volume loss.

Difference between Dermal Fillers and PLLA 

Dermal Fillers like, Replengen, Aessoa etc.and PLLA (Poly-L-Lactic Acid) fillers serve as popular options for aesthetic treatments but function quite differently. HA fillers are gel-like substances that provide immediate volume and smoothness to the treated areas; they primarily address wrinkles and folds by filling them directly and are known for their hydrating properties, generally lasting 6 to 18 months. On the other hand, PLLA fillers act as collagen stimulators, encouraging the skin to produce more collagen over time, offering a more gradual and lasting effect which can endure for up to two years. While HA fillers deliver immediate results, PLLA fillers are more about gradual and long-term improvements, providing a subtle, natural transition to a younger-looking skin.

Seeking Medical Advice

Before opting for PLLA injections, it is critical to consult with a healthcare provider or a licensed practitioner. They can guide you on the appropriate time to use PLLA injections based on your unique circumstances and medical history.