Description

Etrebelle 200mg — PLA + HA Hybrid Filler

Etrebelle 200mg is a hybrid dermal filler from Yooyoung Pharmaceutical Co., Ltd. in Seoul, South Korea, a subsidiary of Cosmo-Korea. It combines poly-D,L-lactide (PLA) microparticles with hyaluronic acid (HA). This pairing gives it both an immediate filling effect and a longer-term collagen-stimulating one.

The Etrebelle line includes two products — Etrebelle 50 and Etrebelle 200 — differing in concentration and intended use. Etrebelle 200 carries the higher concentration, built for facial volumizing and broader improvements to skin elasticity.

At a Glance

Total Composition	200mg per unit
Duration	Up to 2 years
Manufacturer	Yooyoung Pharmaceutical Co., Ltd., South Korea

Main Benefits

• Two-phase action: immediate volumizing from HA, followed by long-term collagen stimulation from PLA
• PLA prevents HA migration: the microparticles add cohesiveness, helping the gel stay in place
• Well-ordered particle structure: supports smooth application and effective volumizing
• Long-lasting results: effects generally last up to 2 years
• Includes needles and cannula: ready for administration out of the box

What’s Inside

Poly-D,L-Lactide (PLA)	170mg
Hyaluronic Acid (Sodium Hyaluronate)	30mg
Packing	Includes needles and cannula
Manufacturer	Yooyoung Pharmaceutical Co., Ltd., South Korea

Yooyoung also produces Etrebelle PN 436.8mg, a related formula that adds polynucleotides (PN) to help manage the inflammatory response to PLA particles.

How Etrebelle Works

Etrebelle works in two distinct phases. Right after injection, the HA hydrogel takes position immediately, physically filling wrinkles and volume-deficient areas. The PLA microparticles support this phase by giving the gel extra cohesiveness. This helps prevent the HA from migrating away from the treatment site.

Around a month later, the second phase begins. As the HA gradually hydrolyzes and breaks down, the PLA microparticles start promoting new collagen production, improving skin elasticity from within. This staged handoff, with HA providing early support while PLA builds the longer-term structure, is what gives Etrebelle both immediate and lasting results.

Who Etrebelle Suits

Practitioners recommend Etrebelle 200mg for patients interested in:

• Facial volumizing and contour correction
• Correcting perioral, nasolabial, and marionette wrinkles
• Addressing facial asymmetry
• Improving age-related sagging and skin laxity
• Smoothing depressed acne scarring

Treatment Areas

Perioral area · Nasolabial folds · Marionette lines · Cheeks and mid-face · Areas with facial asymmetry or volume loss

Administration

A licensed practitioner injects Etrebelle beneath the skin, using the needles or cannula included with the product. Exact technique and depth depend on the treatment area and the degree of correction needed, and should be determined by the treating practitioner.

Precautions

• For use by licensed medical professionals only
• Not recommended during pregnancy or breastfeeding
• Avoid in patients with known hypersensitivity to HA or PLA-based materials
• Avoid in areas with active skin infection or inflammation

Storage & Handling

• Store at room temperature, away from direct light
• Single-use only — do not reuse or resterilize
• For professional use only, by qualified and trained practitioners

Frequently Asked Questions

What is Etrebelle 200mg?
Etrebelle 200mg is a hybrid dermal filler from Yooyoung Pharmaceutical, combining PLA and HA to deliver both immediate volumizing and long-term collagen stimulation.

How is Etrebelle 200mg different from Etrebelle 50?
The two differ in concentration. Etrebelle 200 carries a higher combined dose of PLA and HA, positioning it for more substantial volumizing than Etrebelle 50.

How is Etrebelle 200mg different from Etrebelle PN?
Etrebelle 200mg contains only PLA and HA. Etrebelle PN adds polynucleotides to the formula, which helps manage the inflammatory response to the PLA particles.

How long do results last?
Results generally last up to 2 years, thanks to the combined effect of HA-based volumizing and PLA-driven collagen stimulation.

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