Coretox 100UI
Clostridium botulinum toxin type A · 100 units · lyophilised powder. Formulated without human serum albumin. Manufactured by Medytox Inc, South Korea.
Original price was: $79.90.$59.90Current price is: $59.90.
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Coretox 100 Units is a protein-free botulinum toxin type A from Medytox, free of human serum albumin and animal-derived components, designed to reduce immune resistance risk over repeated treatments. Results last up to 12 months.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
In accordance with applicable U.S. FDA regulations, this product is not available for purchase or shipment to U.S. addresses through this website. Customers in the United States should obtain botulinum toxin products through appropriately licensed and authorized U.S. distribution channels. A valid medical license or registration certificate is required to process any product-related claim.
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Medytox's albumin-free lyophilised toxin
Coretox is a botulinum toxin type A product from Medytox Inc, supplied as a sterile lyophilised white powder in a single 100-unit vial and reconstituted with preservative-free 0.9% sodium chloride before use.
What sets it apart from most lyophilised toxins is its stabiliser system. Where conventional products use human serum albumin — a human blood derivative — Coretox is formulated without albumin, using polysorbate 20, sucrose and L-methionine instead. Medytox describes the formulation as free of complexing proteins and of animal-derived components.
That matters in two practical ways. For patients who ask specifically about blood-derived excipients, the answer here is straightforward. And for practices serving patients with dietary or religious restrictions on animal-derived materials, it removes a conversation that other toxins require.
Medytox also makes Meditoxin and the ready-to-use liquid Innotox. Coretox is the albumin-free lyophilised option in that range — chosen where a practitioner wants to set their own dilution but prefers to avoid albumin.
Stabilised with polysorbate 20, sucrose and L-methionine rather than human serum albumin.
Medytox describes the formulation as free of complexing proteins and of animal-derived components.
Supplied as a powder, so concentration is chosen at the bench to suit the treatment area.
Sits alongside Meditoxin and the ready-to-use liquid Innotox, so one manufacturer covers several preferences.
Why practitioners choose Coretox 100UI
Stabilised with polysorbate 20, sucrose and L-methionine. A direct answer for patients who ask about blood-derived components in an injectable.
Medytox describes the formulation as free of animal-derived material, which removes a conversation for patients with dietary or religious restrictions.
Despite the different stabiliser system, it reconstitutes and stores like any other lyophilised toxin — no change to your existing workflow.
Supplied as a powder rather than a solution, so concentration is set to suit the treatment area.
Aesthetic & therapeutic applications
Areas commonly treated with this product. Approval status differs between markets — always work from the prescribing information registered in the country where you practise.
Vertical lines between the brows, driven by the corrugator supercilii pulling the brows medially and the procerus pulling the glabella down. The one aesthetic indication approved for botulinum toxin type A in nearly every market that registers the class at all.
Lines at the outer eye produced by orbicularis oculi activity. Widely treated in aesthetic practice; whether it is an approved indication for this product depends on your market.
Not an indication as such, but the main clinical reason practitioners select this product specifically — it allows treatment without human serum albumin where a patient has raised that concern.
Horizontal lines produced by frontalis activity. Treatment here is a clinical decision taken by the practitioner within their own regulatory framework.
Botulinum toxin products are prescription-only medicines. Any use outside the indications approved in your jurisdiction is a clinical decision made by the treating practitioner under their own professional judgement and local regulatory framework. Korea Filler Experts supplies the product; nothing here should be read as a recommendation to treat any medical condition.
What is inside Coretox 100UI
| Active substance | Clostridium botulinum toxin type A (Hall strain) |
| Strength | 100 Units per vial |
| Human serum albumin | None |
| Stabilisers | Polysorbate 20, sucrose, L-methionine |
| Pharmaceutical form | Lyophilised white powder for solution for injection |
| Diluent | Preservative-free 0.9% sodium chloride injection (not supplied) |
| Container | Single-use glass vial |
| Route | Intramuscular injection |
| Regulatory status | MFDS approved (Korea). Not FDA approved. |
| Manufacturer | Medytox Inc, South Korea |
| Regulatory class | Prescription-only medicine (professional use) |
Reading the carton
Before you accept a delivery, check four things:
- The lot / batch number on the carton matches the number printed on the vial.
- The expiry date leaves you enough working life — we do not dispatch stock with under 6 months remaining unless agreed in advance.
- The seal is intact and the vial has not been disturbed.
- The carton arrived cold, with the coolant pack still chilled.
Vial looks empty? The contents are freeze-dried under vacuum, so the powder forms a thin film that is hard to see against the glass. This is expected and is not a sign of a short fill.
What makes this formulation different
- No human serum albumin — most lyophilised toxins use albumin, a protein derived from human blood, as the stabiliser. Coretox does not.
- Polysorbate 20 — a non-ionic surfactant used in place of albumin to protect the protein from surface adsorption.
- Sucrose — a bulking agent that supports the structure of the freeze-dried cake.
- L-methionine — an amino acid included to limit oxidative degradation during storage.
Medytox describes the formulation as free of complexing proteins and of animal-derived components. Confirm against the insert supplied with your stock, as labelling varies by market.
How to prepare and use Coretox 100UI
Reference information for licensed practitioners. Reconstitution and administration must follow the prescribing information approved in your market and your own clinical governance procedures.
Step by step
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Inspect the vial
Check the label, lot number and expiry date. The powder should be white and the seal intact.
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Prepare the diluent
Draw the required volume of preservative-free 0.9% sodium chloride injection into a sterile syringe.
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Disinfect the stopper
Wipe the exposed rubber stopper with an alcohol swab and allow it to dry.
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Introduce the diluent slowly
Insert the needle at an angle and let the vacuum draw the saline in. Direct the stream against the vial wall rather than onto the powder.
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Mix gently
Rotate the vial slowly to dissolve the cake. Do not shake vigorously. The solution should be clear, colourless and free of particulates.
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Record and use promptly
Note the reconstitution date and time on the vial, store at 2–8 °C, and use within the period stated in your approved prescribing information.
Dilution reference
| Diluent added | Units per 0.1 mL | Total volume |
|---|---|---|
| 1.0 mL | 10.0 U | 1.0 mL |
| 2.0 mL | 5.0 U | 2.0 mL |
| 2.5 mL | 4.0 U | 2.5 mL |
| 4.0 mL | 2.5 U | 4.0 mL |
| 5.0 mL | 2.0 U | 5.0 mL |
Administration notes
Coretox reconstitutes and handles like any conventional lyophilised toxin. The different stabiliser system does not change the preparation workflow.
Materials needed: preservative-free 0.9% sterile saline, a sterile syringe with a fine-gauge needle, gloves and alcohol swabs. None of these are supplied with the vial.
- Units of botulinum toxin are product-specific. Do not convert or substitute units between brands.
- Dose per site, total dose and injection technique must follow the prescribing information approved in your market.
- Draw reconstituted product immediately before injection.
- Treatment intervals should not be shortened below the minimum stated in the prescribing information.
After treatment
- Avoid rubbing or massaging the treated area for at least 24 hours
- Stay upright and avoid lying down for 4 to 6 hours
- Avoid strenuous exercise for 24 to 48 hours
- Avoid saunas, hot tubs and excessive sun exposure for at least 24 hours
- Mild redness, swelling or bruising can occur and usually settles within a few days
Storing and handling Coretox 100UI
Store refrigerated at 2–8 °C in the original carton, protected from light. Do not freeze. Always work to the expiry date printed on the carton.
Keep at 2–8 °C and use within the period stated in your approved prescribing information. Do not freeze reconstituted solution. Single-patient use only.
Transfer stock into a monitored medical refrigerator on arrival and keep a temperature log. If a shipment arrives warm, photograph the packaging and contact us before putting it into clinical service.
Do not use the vial if the powder is discoloured, if the reconstituted solution is cloudy or contains particles, if the expiry date has passed, or if the cold chain is known to have been broken. Dispose of unused product and used vials as clinical waste in line with local requirements.
What's included with Coretox 100UI
Diluent (0.9% sodium chloride injection), syringes and needles are not supplied with this product and must be sourced separately.
Coretox 100UI — frequently asked questions
What is Coretox 100UI?
Coretox 100UI is a botulinum toxin type A product manufactured by Medytox Inc. in South Korea. It is supplied as a sterile freeze-dried white powder in a single 100-unit vial and reconstituted with preservative-free 0.9% sodium chloride before injection by a licensed practitioner.
What does "albumin-free" mean here?
Most lyophilised botulinum toxins use human serum albumin — a protein derived from human blood — as the stabiliser. Coretox uses polysorbate 20, sucrose and L-methionine instead.
In practice this matters most as an answer to a patient question. Some patients ask specifically about blood-derived components in an injectable, and with this product the answer is that there are none.
Is it suitable for patients avoiding animal-derived products?
Medytox describes the formulation as free of animal-derived components. For patients with dietary or religious restrictions this is worth confirming against the insert supplied with your specific stock, since labelling varies between markets.
Does the different formulation change how I handle it?
No. It reconstitutes, stores and is injected like any conventional lyophilised toxin — 2–8 °C storage, preservative-free saline, practitioner-set dilution. The stabiliser system differs; the workflow does not.
How does Coretox differ from Meditoxin and Innotox?
All three are Medytox products. Meditoxin is a conventional lyophilised toxin stabilised with albumin. Innotox is a ready-to-use liquid, also albumin-free, at a fixed 4 units per 0.1 mL. Coretox sits between them: albumin-free like Innotox, but lyophilised like Meditoxin, so you keep control over dilution.
Is Coretox FDA approved?
No. It is cleared by Korea’s Ministry of Food and Drug Safety for the Korean market. It does not hold United States FDA approval, and availability and permitted use vary considerably by country — confirm your own regulatory position before ordering.
Can I substitute Coretox units for another brand's units?
No. Units of botulinum toxin are specific to each product and are not interchangeable between brands. Dosing must be taken from the prescribing information for the product in your hand.
What shelf life will my stock have?
We do not dispatch stock with less than six months of remaining shelf life unless you have specifically agreed to it. If you need a particular expiry window, tell us before you order and we will allocate accordingly.
What happens if my shipment arrives warm?
Do not use it. Photograph the outer box, the insulated liner, the coolant packs and the vial carton, and contact us the same day with your order number. We will review the cold-chain evidence and arrange a replacement where the failure occurred in transit.
Who is allowed to buy this product?
Botulinum toxin is a prescription-only medicine. Purchase and use are restricted to licensed healthcare professionals qualified to prescribe or administer injectable prescription medicines in their jurisdiction, with appropriate training in the relevant anatomy and injection technique. We do not sell to consumers.
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