Description

Neuronox 100UI — Botulinum Toxin Type A

Neuronox 100UI is Medytox’s original botulinum toxin type A formulation, first approved by Korea’s Ministry of Food and Drug Safety in 2006. It was the first botulinum toxin brand developed and marketed in Korea. Medytox now sells it in more than 60 countries under several names, including Meditoxin, Botulift, Cunox, and Siax.

Medytox was founded by scientists from the Korea Advanced Institute of Science and Technology (KAIST). They worked with the same Clostridium botulinum Hall A-hyper strain used to develop Allergan’s original Botox. Published genetic analysis has confirmed this shared strain origin, a distinction that sets Neuronox apart from several other Korean toxin brands.

At a Glance

Units per Vial	100 units
Onset	Often cited as 1–2 days
Duration	3–6 months
Shelf Life	36 months from manufacturing date
Manufacturer	Medytox Inc., South Korea

Main Benefits

• Shared strain with Botox: built on the same Hall A-hyper strain, confirmed through genetic analysis
• Fast onset: often cited as visible within 1 to 2 days
• Low diffusion: stays localized to the treatment area, supporting natural-looking results
• Directly transferable dosing: commonly administered at a 1:1 ratio with Botox, so clinical protocols carry over

What’s Inside

Active Ingredient	Clostridium botulinum toxin type A — 100 units
Stabilizer	Human serum albumin — 0.5mg
Additive	Sodium chloride — 0.9mg
Format	Lyophilized powder, single-dose vial
Manufacturer	Medytox Inc., South Korea

Packaging and included accessories vary by supplier — check your specific listing for exact kit contents.

Mechanism of Action

Neuronox blocks neuromuscular transmission by binding to acceptor sites on motor nerve terminals. Once inside the nerve terminal, it cleaves SNAP-25, a protein essential for releasing acetylcholine from nerve endings. Because this release no longer occurs normally, the treated muscle experiences partial, localized denervation. As a result, muscle activity in that area decreases. This smooths the overlying skin’s dynamic wrinkles.

Preparation & Dilution

Reconstitute Neuronox with 0.9% sodium chloride injection, then mix gently by swirling the vial rather than shaking it.

Saline Added (100U vial)	Resulting Concentration
1.0mL	10 units per 0.1mL
2.0mL	5 units per 0.1mL
2.5mL	4 units per 0.1mL
4.0mL	2.5 units per 0.1mL

Administer the reconstituted solution within 24 hours, and store it refrigerated at 2–8°C in the meantime.

Treatment Areas

• Glabellar frown lines, forehead lines, and crow’s feet
• Platysmal neck bands (“turkey neck”)
• Masseter, temporalis, calf, and deltoid muscle reduction for contouring
• Hyperhidrosis of the palms, calves, armpits, and thighs

Dosage & Technique

The exact dosage and number of injection sites should reflect each patient’s muscle size, location, and the severity of the condition being treated. Neuronox is often used at a 1:1 dosing ratio with Botox. Because of this, practitioners familiar with Botox protocols can generally apply similar dosing when switching to Neuronox. Even so, a qualified practitioner should always confirm the appropriate plan for each patient.

Precautions

• For use by licensed medical professionals only
• Contraindicated in patients with neuromuscular junction disorders, such as myasthenia gravis
• Contraindicated during pregnancy or breastfeeding, or where safety hasn’t been established
• Avoid in patients with active infection, inflammation, or open wounds at the injection site
• Use caution in patients taking medications with neuromuscular interactions

Storage & Handling

• Store refrigerated at 2–8°C
• Do not freeze
• Use within 24 hours after reconstitution

Botulinum toxin type A is a prescription medical product for use by licensed healthcare professionals only.

Frequently Asked Questions

What is Neuronox 100UI?
Neuronox 100UI is Medytox’s original botulinum toxin type A product, sharing the same Hall A-hyper strain as Allergan’s Botox and sold internationally under several names.

Is Neuronox the same as Meditoxin?
Yes. Medytox markets this identical formulation as Neuronox in export markets and as Meditoxin, Botulift, Cunox, and Siax in others, depending on the region.

Can Neuronox treat masseter or calf muscles for contouring?
Yes. Practitioners commonly use it to reduce muscle volume in the masseter, temporalis, calf, and deltoid for facial and body contouring.

How does Neuronox dosing compare to Botox?
It’s commonly administered at a 1:1 ratio with Botox, allowing practitioners to apply familiar dosing protocols when switching between the two.

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