Description

Meditoxin 100UI — Botulinum Toxin Type A

Meditoxin 100UI is Medytox’s original botulinum toxin type A product line, first approved in South Korea in the mid-2000s. Medytox distributes this same formulation internationally under several regional names, including Siax, Botulift, Cunox, and Neuronox.

Multiple clinical studies have found Meditoxin comparable to OnabotulinumtoxinA (Botox) in both efficacy and safety. Because it carries a high molecular weight, it also shows minimal diffusion, which makes it well suited to delicate facial areas like the eyes and lips.

At a Glance

Units per Vial	100 units
Format	Lyophilized white powder
Global Names	Siax, Botulift, Cunox, Neuronox
Shelf Life	36 months from manufacturing date
Manufacturer	Medytox Inc., South Korea

Main Benefits

• Clinically validated: comparable efficacy and safety to Botox across multiple studies
• Minimal diffusion: high molecular weight helps keep the effect localized, suiting delicate areas
• Globally established: distributed in 27 countries under various regional names, with more registrations in progress
• Versatile use: suits both cosmetic wrinkle correction and therapeutic applications

What’s Inside

Active Ingredient	Clostridium botulinum toxin type A complex — 100 units
Stabilizer	Human serum albumin — 0.5mg
Additive	Sodium chloride — 0.9mg
Format	Lyophilized powder, single-dose vial
Manufacturer	Medytox Inc., South Korea

Packaging and included accessories vary by supplier — check your specific listing for exact kit contents.

Mechanism of Action

Meditoxin blocks the release of acetylcholine at the neuromuscular junction. As a result, the treated muscle experiences temporary, localized relaxation. This smooths dynamic wrinkles caused by repeated facial movement, and it also helps ease involuntary muscle activity in therapeutic applications.

Preparation & Dilution

Meditoxin ships as a powder under slight vacuum inside a glass ampoule. Because of this, the vial can sometimes look empty — this is normal, and the full dose remains present. Reconstitute it gently with 0.9% sterile saline, injecting the diluent slowly into the vial rather than shaking it, since vigorous shaking can reduce potency significantly.

Saline Added (100U vial)	Resulting Concentration
1.0mL	10 units per 0.1mL
2.0mL	5 units per 0.1mL
2.5mL	4 units per 0.1mL
4.0mL	2.5 units per 0.1mL

1. Inspect the vial for a clear, uncontaminated appearance before reconstituting
2. Slowly inject the saline into the vial, avoiding vigorous shaking
3. Label the vial with the date, time, dilution ratio, and your initials for traceability
4. Store refrigerated at 2–8°C and use within 24 hours
5. Discard the solution if it appears cloudy, since this indicates protein aggregation

Treatment Areas & Indications

• Glabellar lines (vertical creases between the eyebrows)
• Forehead wrinkles and crow’s feet
• Wrinkles near the mouth and neck (platysmal bands)
• Blepharospasm
• TMJ-related conditions and stroke-related muscle spasticity

Dosage & Technique

For glabellar wrinkles, practitioners typically inject the reconstituted solution (100U/2.5mL) using a 30-gauge needle across the corrugator and procerus muscles. For blepharospasm, a common approach uses a 27–30 gauge needle to deliver 1.25 to 2.5 units (0.05 to 0.1mL) per site into the medial and lateral pre-tarsal orbicularis oculi muscles, without EMG guidance. A qualified practitioner should always determine the exact dose based on the patient’s condition.

Onset & Duration

Individual response varies by metabolism, antibody status, and lifestyle factors. If a particular toxin doesn’t work well for a given patient, this doesn’t necessarily indicate a defective batch — practitioners often need to find the product that works best through experience with each patient.

Precautions

• For use by licensed doctors or cosmetologists trained in aesthetic medicine only
• Contraindicated in patients with neuromuscular junction disorders
• Contraindicated during pregnancy or breastfeeding
• Avoid in patients with active infection at the injection site

Storage & Handling

• Store refrigerated at 2–8°C
• Do not freeze
• Use the reconstituted solution within 24 hours, even if refrigerated
• Discard any unused solution rather than saving it for later use

Botulinum toxin type A is a prescription medical product for use by licensed healthcare professionals only.

Frequently Asked Questions

What is Meditoxin 100UI?
Meditoxin 100UI is Medytox’s original botulinum toxin type A product, used for facial wrinkle correction and several therapeutic applications, including blepharospasm.

Why does the vial look empty?
Because Meditoxin ships as a powder under slight vacuum, very little is visible inside the ampoule. The full dose remains present and dissolves completely once reconstituted.

Is Meditoxin the same as Neuronox?
Yes. Medytox markets this formulation under several regional names, including Neuronox, Siax, Botulift, and Cunox, depending on the market.

How is Meditoxin different from Innotox?
Both come from Medytox, but Meditoxin is a lyophilized powder requiring reconstitution, while Innotox is a ready-to-use liquid formulation.

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