Description

Meditoxin 200UI — Botulinum Toxin Type A

Meditoxin 200UI is Medytox’s original botulinum toxin type A product line, first approved in South Korea in the mid-2000s. This vial delivers double the toxin content of the standard 100-unit option. As a result, it suits larger areas or combined treatment sessions. Medytox distributes this same formulation internationally under several regional names, including Siax, Botulift, Cunox, and Neuronox.

Multiple clinical studies have found Meditoxin comparable to OnabotulinumtoxinA (Botox) in both efficacy and safety. Because it carries a high molecular weight, it also shows minimal diffusion, which makes it well suited to delicate facial areas like the eyes and lips.

At a Glance

Units per Vial	200 units
Format	Lyophilized white powder
Global Names	Siax, Botulift, Cunox, Neuronox
Shelf Life	36 months from manufacturing date
Manufacturer	Medytox Inc., South Korea

Main Benefits

• Covers larger areas per vial: 200 units reduces the need for multiple vials in bigger sessions
• Clinically validated: comparable efficacy and safety to Botox across multiple studies
• Minimal diffusion: high molecular weight helps keep the effect localized, suiting delicate areas
• Versatile use: suits both cosmetic wrinkle correction and larger-scale therapeutic applications

What’s Inside

Active Ingredient	Clostridium botulinum toxin type A complex — 200 units
Stabilizer	Human serum albumin
Additive	Sodium chloride
Format	Lyophilized powder, single-dose vial
Manufacturer	Medytox Inc., South Korea

Packaging and included accessories vary by supplier — check your specific listing for exact kit contents.

Mechanism of Action

Meditoxin blocks the release of acetylcholine at the neuromuscular junction. As a result, the treated muscle experiences temporary, localized relaxation. This smooths dynamic wrinkles caused by repeated facial movement, and it also helps ease involuntary muscle activity in therapeutic applications.

Preparation & Dilution

Meditoxin ships as a powder under slight vacuum inside a glass ampoule. Because of this, the vial can sometimes look empty. This is normal, and the full dose remains present. Reconstitute it gently with 0.9% sterile saline, injecting the diluent slowly into the vial rather than shaking it. Vigorous shaking can reduce potency significantly.

Saline Added (200U vial)	Resulting Concentration
2.0mL	10 units per 0.1mL
4.0mL	5 units per 0.1mL
5.0mL	4 units per 0.1mL
8.0mL	2.5 units per 0.1mL

1. Inspect the vial for a clear, uncontaminated appearance before reconstituting
2. Slowly inject the saline into the vial, avoiding vigorous shaking
3. Label the vial with the date, time, dilution ratio, and your initials for traceability
4. Store refrigerated at 2–8°C and use within 24 hours
5. Discard the solution if it appears cloudy, since this indicates protein aggregation

Treatment Areas & Indications

• Glabellar lines (vertical creases between the eyebrows)
• Forehead wrinkles and crow’s feet
• Wrinkles near the mouth and neck (platysmal bands)
• Blepharospasm
• Pediatric cerebral palsy-related muscle spasticity
• TMJ-related conditions and stroke-related muscle spasticity

Dosage & Technique

For glabellar wrinkles, practitioners typically inject the reconstituted solution at a 100U/2.5mL ratio using a 30-gauge needle across the corrugator and procerus muscles. Because the 200-unit vial holds more total volume, practitioners often use it for sessions that combine multiple treatment areas.

For pediatric cerebral palsy, a reconstituted solution is injected using a 26–30 gauge needle into the medial and lateral heads of the gastrocnemius muscle. A typical reference dose is 4 units per kilogram of body weight for the affected muscle in hemiplegic patients. As always, a qualified practitioner should determine the exact dose and technique based on the patient’s condition.

Onset & Duration

Individual response varies by metabolism, antibody status, and lifestyle factors. If a particular toxin doesn’t work well for a given patient, this doesn’t necessarily indicate a defective batch. Instead, practitioners often need to find the product that works best through experience with each patient.

Precautions

• For use by licensed doctors or cosmetologists trained in aesthetic medicine only
• Contraindicated in patients with neuromuscular junction disorders
• Contraindicated during pregnancy or breastfeeding
• Avoid in patients with active infection at the injection site
• Pediatric dosing requires particular care and should follow established clinical protocols

Storage & Handling

• Store refrigerated at 2–8°C
• Do not freeze
• Use the reconstituted solution within 24 hours, even if refrigerated
• Discard any unused solution rather than saving it for later use

Botulinum toxin type A is a prescription medical product for use by licensed healthcare professionals only.

Frequently Asked Questions

What is Meditoxin 200UI?
Meditoxin 200UI is Medytox’s original botulinum toxin type A product, offering double the standard unit count for larger treatment sessions or therapeutic use.

Who is the 200UI vial best suited for?
Practitioners treating larger areas, multiple facial zones, or therapeutic applications like pediatric spasticity often prefer it, since it reduces the need for multiple vials.

Is Meditoxin the same as Neuronox?
Yes. Medytox markets this formulation under several regional names, including Neuronox, Siax, Botulift, and Cunox, depending on the market.

How is Meditoxin 200UI different from the 100UI version?
Both share the same formulation and manufacturer. The 200UI vial simply contains double the toxin units, reducing the need for multiple vials in larger sessions.

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