AestheFill 200mg
Poly-D,L-lactic acid (PDLLA) collagen biostimulator · 200 mg per vial · lyophilised powder · Regen Biotech, South Korea.
Original price was: $285.00.$265.00Current price is: $265.00.
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- AestheFill 200mg is a PDLLA collagen biostimulator from Regen Biotech, chemically distinct from Sculptra’s PLLA formula. It stimulates natural collagen production for facial volume loss and deep folds, with results lasting up to 2 years.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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AestheFill 200mg: a PDLLA collagen biostimulator from Regen Biotech
AestheFill 200mg is a poly-D,L-lactic acid (PDLLA) collagen biostimulator from Regen Biotech Inc. in South Korea. Each vial holds 200 mg of lyophilised powder: 154 mg PDLLA and 46 mg carboxymethylcellulose (CMC). It is reconstituted with sterile water before injection, and the listed volume is 8 mL.
PDLLA is the D,L isomer of lactic acid polymer, which is different from the PLLA used in other collagen stimulators, and this affects how it behaves and degrades in tissue. AestheFill does not add immediate volume. It is used to prompt the body’s own collagen production, so results build gradually. The listing gives a duration of up to 2 years after a full treatment series. It is for use by licensed professionals only.
Poly-D,L-lactic acid, a biodegradable collagen-stimulating polymer.
Not a volume filler: results build over weeks and a series.
Lyophilised powder, 200 mg in total.
Listed as CE certified by the manufacturer. Not FDA-approved.
About AestheFill 200mg
Uses the D,L isomer of lactic acid polymer, which differs from PLLA in composition and degradation behaviour.
Works by activating fibroblasts to produce collagen rather than adding bulk at injection.
The PDLLA is broken down into water and carbon dioxide, which the body clears.
The listing gives up to 2 years after a full treatment series, which varies by patient.
Treatment areas and indications
Areas and concerns where PDLLA collagen biostimulators are used, as listed on our previous page. Approved indications differ by market.
Sunken cheeks, cheekbones and temples.
Smoothing of deeper folds from within.
Volume and contour of the forehead.
A delicate area that needs specific training.
Correction of creases and dimples of the chin.
AestheFill is an injectable medical product. Which indications are permitted and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training.
AestheFill 200mg specification
| Product type | PDLLA collagen biostimulator |
| Poly-D,L-lactic acid (PDLLA) | 154 mg |
| Carboxymethylcellulose (CMC) | 46 mg |
| Total per vial | 200 mg |
| Format | Lyophilised powder |
| Reconstitution (as listed) | 8 mL sterile water |
| Packing | 1 vial per box |
| Duration (as listed) | Up to 2 years after a full treatment series |
| Regulatory status (manufacturer's statement) | CE certified; not FDA-approved |
| Storage | Room temperature, away from direct light |
| Manufacturer | Regen Biotech Inc, South Korea |
| SKU | 06002 |
Before you order
- Regulatory status. The finished product is CE certified and is not FDA-approved. PDLLA as a raw material has held FDA GRAS (Generally Recognized As Safe) status since 1984; this refers to the material itself, not to FDA approval of AestheFill. Confirm the status in the country where you practise.
- Every box ships in its original packaging with the lot number and expiry date.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
Priced per box (1 vial), with quantity discounts at five, ten and twenty boxes.
What each component does
Poly-D,L-lactic acid (PDLLA), 154 mg
PDLLA is a biodegradable polymer. Once injected, the particles are described as prompting fibroblasts to produce new collagen around the treated area. The polymer is then broken down into water and carbon dioxide, which the body clears.
Carboxymethylcellulose (CMC), 46 mg
CMC helps keep the particles suspended in the reconstituted product.
PDLLA and PLLA
PDLLA and PLLA are related but chemically different materials. AestheFill is a PDLLA product.
FDA GRAS status of the material
PDLLA as a raw material has held FDA GRAS (Generally Recognized As Safe) status since 1984. This refers to the material itself, not to FDA approval of the finished AestheFill product, which is CE certified rather than FDA-approved.
Approved indications differ by country. Read the manufacturer’s instructions for use.
How AestheFill is used
Reference information for trained practitioners. PDLLA products have specific preparation and technique requirements. The manufacturer’s instructions for use and your training take precedence over this page, including reconstitution volume, needle or cannula, plane and volume per area.
Step by step
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Assess and consent
Confirm the aim is gradual improvement, not immediate volume. Review medical history, autoimmune disease, keloid scarring, medication and previous fillers. Explain that results build over time.
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Reconstitute
Reconstitute the powder with sterile water shortly before use, following the manufacturer’s instructions and standard aseptic technique. The listed volume is 8 mL.
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Prepare the skin
Cleanse the skin thoroughly and remove make-up.
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Inject as taught
Place the product in the dermal or subdermal layer as stated in the instructions for use and your training, using the recommended cannula or needle. Inject slowly with low pressure.
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Do not over-correct
A biostimulator is not a filler. Early swelling can look like a result and settles within days.
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Review
Assess the response over time and decide on any further treatment as a clinical decision.
Administration notes
Be selective about sites. Delicate areas such as the under-eye hollows need specific training. Know how to recognise and manage nodules and vascular events.
- Single use. Do not reuse or resterilise. Discard any remainder.
- Do not inject into infected, inflamed or broken skin.
- Dispose of needles and cannulas into a sharps container in line with local clinical waste rules.
After treatment
- Avoid strenuous activity, excessive sun exposure and extreme temperatures for 24 to 48 hours
- Avoid touching the injection sites, to reduce infection risk
- Avoid saunas, steam rooms and swimming pools for a period after treatment
- Seek urgent review for severe pain, blanching, skin colour change or a lump that grows or becomes tender
Storing and handling AestheFill
Store at room temperature, away from direct light.
Use before the expiry date, and only if the packaging and vial are intact.
Reconstitute shortly before use, following the manufacturer’s instructions. Single patient, single session. Do not retain or reuse any remainder.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials, syringes and needles as clinical waste in line with local requirements.
What's included with AestheFill
Sterile water, syringes, needles, cannulas and anaesthetic are not supplied.
AestheFill 200mg — frequently asked questions
What is AestheFill 200mg?
A PDLLA collagen biostimulator from Regen Biotech, supplied as a 200 mg lyophilised powder in one vial per box, designed to restore facial volume and smooth wrinkles by prompting the body’s own collagen.
Is AestheFill a PLLA product?
No. It uses PDLLA (poly-D,L-lactic acid), a related but chemically different material from PLLA, with different degradation behaviour.
Is it FDA-approved?
The finished product carries CE certification rather than FDA approval. PDLLA as a raw material has held FDA GRAS (Generally Recognized As Safe) status since 1984, but that applies to the material, not to the finished device.
How long do the results last?
The listing gives up to 2 years following a complete treatment series. It varies by patient.
How is it prepared?
It is a lyophilised powder reconstituted with sterile water shortly before use. The listed volume is 8 mL, and the instructions for use apply.
Which areas is it used on?
The listing names the forehead, cheeks and cheekbones, temples, nasolabial folds, marionette lines, under-eye hollows, and chin creases and dimples. Delicate areas need specific training.
Who can buy and use this product?
Injectable products are for administration by licensed healthcare practitioners trained in injection technique. We supply qualified professionals and do not sell to consumers.
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