Description

ASCE+ SRLV — Plant Exosome Skin Regeneration Kit by ExoCoBio

ASCE+ SRLV is a two-vial exosome system from ExoCoBio in South Korea. Rather than using mammalian stem-cell-derived exosomes, ExoCoBio builds it around Rosa damascena (Damask rose) callus-derived extracellular vesicles. The company developed the kit using its proprietary ExoSCRT™ isolation and purification technology, and the brand received Korea’s IR52 Jang Young-sil innovation award in 2020.

The extracellular vesicles come from a plant source rather than mammalian cell culture. Because of this, ASCE+ SRLV avoids some of the sourcing and disease-transmission questions associated with animal-derived exosome products. That said, exosome-based cosmetic products as a category currently sit in a serious regulatory gray area in several markets — a topic we cover in more detail below.

At a Glance

Core Ingredient	Rosa damascena callus extracellular vesicles (plant-derived)
Format	2-vial system: lyophilized powder + diluent
Diluent Volume	5mL, HA-buffered
Manufacturer	ExoCoBio, South Korea

Main Benefits

• Plant-derived exosomes: vegan, non-animal origin, avoiding mammalian-source sourcing questions
• Multi-active reconstitution fluid: the diluent itself contains NAD+, retinol, and vitamin C
• Two-stage filtration: removes proteins and cell debris during manufacturing for a cleaner formulation
• Flexible delivery: suits both microchannel (microneedling) and mesotherapy application
• Backed by proprietary technology: ExoCoBio developed the ExoSCRT™ isolation process specifically for this line

What’s Inside

Vial 1 (Lyophilized Powder)	Rosa damascena callus extracellular vesicles, NAD+, retinol, ascorbic acid, glutathione, Copper Tripeptide-1, palmitoyl peptides, 19 amino acids, 4 coenzymes
Vial 2 (Diluent)	5mL HA-buffered solution
Manufacturer	ExoCoBio, South Korea

Important Regulatory Context

The US FDA has not approved exosome-based cosmetic and aesthetic products, as a category, for any cosmetic or therapeutic use. The FDA issued a formal Public Safety Notification on exosome products after multiple reports of serious adverse events in treated patients. The agency has also sent warning letters to several US companies marketing exosome products, including as recently as 2025.

The FDA has also stated that marketing an exosome product as “cosmetic” doesn’t exempt it from drug regulation if a company promotes the product for tissue regeneration or healing effects. Because of this, practitioners and buyers should independently verify the current legal status of exosome-based products in their own country or state before purchase, marketing, or use. They shouldn’t treat Korean regulatory status as an indicator of approval elsewhere.

How ASCE+ SRLV Works

Extracellular vesicles, commonly called exosomes, are nanometer-sized packages that cells naturally release to communicate with each other. Specifically, they carry proteins, lipids, and genetic material. In ASCE+ SRLV, these vesicles come from cultured Damask rose callus tissue rather than animal or human cell sources.

The diluent used to reconstitute the powder is formulated as an active concentrate in its own right. NAD+ supports cellular energy processes, retinol is associated with keratinocyte turnover, and ascorbic acid plays a role in collagen biosynthesis. Once mixed, practitioners deliver the combined solution either through microchannels created by microneedling or through direct mesotherapy injection.

Who ASCE+ SRLV Suits

Practitioners who choose to use ASCE+ SRLV, where locally permitted, typically consider it for patients interested in:

• General skin tone and texture improvement
• Fine lines and hydration support
• Patients specifically seeking a vegan or non-animal-derived option

Treatment Areas

Face — applied via microneedling or mesotherapy

Administration

Practitioners mix Vial 1 and Vial 2 immediately before use. They then deliver the resulting solution either topically through microchannels created by microneedling, or via mesotherapy injection, depending on practitioner preference and local regulations.

Precautions

• Confirm current local and national regulatory status before purchase or use — exosome products are not FDA-approved, and some jurisdictions restrict or prohibit them
• For use by licensed medical or aesthetic professionals only, where legally permitted
• Not recommended during pregnancy or breastfeeding
• Avoid in patients with known hypersensitivity to any formula component

Storage & Handling

• Store as directed by the manufacturer, protected from light
• Single-use only — do not reuse or resterilize

Frequently Asked Questions

What is ASCE+ SRLV?
Specifically, ASCE+ SRLV is a two-vial exosome kit from ExoCoBio, using plant-derived extracellular vesicles from Damask rose callus tissue, combined with an active diluent for skin regeneration purposes.

Is ASCE+ SRLV FDA-approved?
No. No exosome-based cosmetic or aesthetic product currently holds FDA approval for any use. Indeed, the FDA has issued safety notifications and warning letters for this product category, following reports of adverse events.

How is ASCE+ SRLV different from mammalian-derived exosome products?
It uses plant-derived extracellular vesicles from Rosa damascena callus tissue rather than exosomes sourced from animal or human stem cell culture, addressing vegan-sourcing preferences.

Does “Gold” or “Silver” labeling change the formula?
No. SRLV-S (Silver) refers to the Korean domestic market version, and SRLV (Gold) refers to the export version. The active formulation is the same across both.

---

Buy ASCE+ SRLV online from Korea Filler Experts, a trusted wholesale supplier of premium aesthetic products, available in set or box packing. We ship worldwide.