Etrebelle PN 436.8mg
PLA + polynucleotide (PN) + hyaluronic acid hybrid skin booster · 436.8 mg · Yooyoung Pharmaceutical, South Korea.
$117.90
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- Etrebelle PN is a hybrid skin booster from Yooyoung Pharmaceutical combining PLA, PN, and Hyaluronic Acid. It targets skin firmness, hydration, and regeneration through three complementary mechanisms rather than volume alone.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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Etrebelle PN 436.8mg: a PLA, PN and HA hybrid skin booster
Etrebelle PN is a hybrid skin booster from Yooyoung Pharmaceutical in South Korea. It combines polylactic acid (PLA), polynucleotide (PN) and hyaluronic acid (HA) in a single formula with a total content of 436.8 mg. Rather than focusing only on immediate volume, it is aimed at overall skin quality: firmness, hydration and resilience.
Each ingredient has a different role. PLA is a biodegradable polymer used in collagen biostimulators. PN is described as supporting skin regeneration. HA gives hydration and smoothness. Because the three act on different timelines, results build gradually. Yooyoung Pharmaceutical has manufactured pharmaceutical and injectable products since 1975 under GMP. It is for use by licensed professionals only.
A biodegradable polymer used to support collagen over time.
Described as supporting skin regeneration.
Gives hydration and a smoother look.
Yooyoung Pharmaceutical has made injectables since 1975.
About Etrebelle PN 436.8mg
The formula is aimed at firmness, hydration and resilience of the skin.
PLA, PN and HA are combined in one 436.8 mg formula, so there is no need to layer separate products.
Hydration appears relatively soon, while collagen-related firmness continues to develop over the following weeks.
Etrebelle 200mg is the PLA + HA version without PN. Etrebelle PN adds polynucleotide to that base.
Treatment areas and indications
Concerns where PLA + PN + HA skin boosters are used. All are skin-quality concerns. Approved indications differ by market.
Skin that has lost firmness and resilience.
Skin that looks dry or lacks radiance.
Texture that looks rough or uneven.
General interest in comprehensive skin-quality improvement.
Etrebelle PN is an injectable medical product. Which indications are permitted and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training.
Etrebelle PN 436.8mg specification
| Product type | PLA + PN + HA hybrid skin booster |
| PLA (polylactic acid) | Supports collagen over time |
| PN (polynucleotide) | Supports skin regeneration |
| HA (hyaluronic acid) | Hydration and smoothness |
| Total content | 436.8 mg |
| Storage | Room temperature |
| Manufacturer | Yooyoung Pharmaceutical Co, Ltd, South Korea |
| SKU | 06025 |
Before you order
- Check local rules. Classification and approval status differ between markets. Confirm what you may import and use where you practise.
- Every unit ships in its original packaging with the lot number and expiry date.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
Priced per unit as listed, with quantity discounts at five, ten and twenty units.
What each component does
Polylactic acid (PLA)
PLA is a biodegradable, biocompatible polymer. It is broken down by the body into water and carbon dioxide, which are cleared through normal metabolism. In collagen biostimulators it is used to prompt the body’s own collagen over time.
Polynucleotide (PN)
Polynucleotides are chains of nucleotides, usually derived from DNA. In skin boosters they are described as supporting skin regeneration.
Hyaluronic acid (HA)
HA binds water and gives hydration and a smoother look.
Approved indications differ by country. Read the manufacturer’s instructions for use.
How Etrebelle PN is used
Reference information for trained practitioners. The manufacturer’s instructions for use and training take precedence over this page, including preparation, technique, depth and volume.
Step by step
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Assess and consent
Review medical history, allergies, autoimmune disease, scarring tendency, medication and previous treatments. Explain that results build gradually and that this is a skin-quality product.
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Prepare the skin
Remove make-up and cleanse thoroughly. Apply topical anaesthetic if required.
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Prepare the product
Inspect the packaging, seal and expiry. Prepare the product exactly as stated in the instructions for use, and use it immediately after opening.
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Treat as taught
Use the method, depth and technique stated in the instructions for use and your training.
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Review
Assess the response and decide on any follow-up treatment as a clinical decision.
Administration notes
Do not over-correct. A product of this kind builds its effect gradually, so adding extra product to force an immediate change can lead to lumps or an over-corrected result.
- Single use. Do not reuse or resterilise. Use immediately upon opening.
- Do not use in infected, inflamed or broken skin.
- Know how to recognise and manage nodules and vascular events.
- Dispose of needles and sharps into a sharps container in line with local clinical waste rules.
After treatment
- Redness, swelling, tenderness and bruising are common and settle within days
- Follow the post-treatment advice in the instructions for use and your clinic’s protocol
- Seek urgent review for severe pain, blanching, skin colour change or a lump that grows or becomes tender
Storing and handling Etrebelle PN
Store at room temperature.
Use before the expiry date, and only if the packaging is intact.
Use immediately upon opening. Single patient, single session. Do not retain or reuse any remainder.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used items and needles as clinical waste in line with local requirements.
What's included with Etrebelle PN
Needles, syringes and topical anaesthetic are not supplied unless stated in the manufacturer’s pack.
Etrebelle PN 436.8mg — frequently asked questions
What is Etrebelle PN 436.8mg?
A hybrid skin booster from Yooyoung Pharmaceutical combining PLA, PN and HA in a single 436.8 mg formula.
How is it different from a standard HA filler?
It is aimed at overall skin quality rather than volume alone. It combines collagen support (PLA), regeneration support (PN) and hydration (HA).
How is it different from Etrebelle 200mg?
Etrebelle 200mg contains PLA and HA only. Etrebelle PN adds polynucleotide for broader skin regeneration support.
Who is it suited to?
Patients concerned about reduced elasticity and firmness, dehydrated or dull-looking skin, uneven texture or visible signs of ageing.
How should it be stored?
At room temperature. Use it immediately upon opening, and do not reuse.
Who can buy and use this product?
Injectable products are for administration by licensed healthcare practitioners trained in the technique. We supply qualified professionals and do not sell to consumers.





