Proluma 365mg
High-purity poly-L-lactic acid (PLLA) collagen biostimulator · 365 mg per vial · Genèse Labs.
Original price was: $190.90.$134.90Current price is: $134.90.
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Proluma PLLA is a CE-certified deep collagen biostimulator from Genèse Labs, formulated with high-purity poly-L-lactic acid for advanced volume loss and facial contouring. It suits patients in their 40s–60s, with results lasting 24 months or more.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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Proluma 365mg: a deep-plane PLLA collagen biostimulator from Genèse Labs
Proluma PLLA is an injectable collagen stimulator from Genèse Labs, formulated with high-purity poly-L-lactic acid (PLLA) with carboxymethylcellulose (CMC) and mannitol as carrier and stabilising components. Each vial contains 365 mg. Its highly crystalline microspheres measure 40 to 60 μm. The product is listed as CE certified.
Unlike hyaluronic acid fillers, which add volume at the time of injection and fade as the HA is absorbed, a PLLA product is used to prompt the body’s own collagen over an extended period, so results build gradually. Proluma PLLA is listed for deeper volume loss and structural facial support, with typical areas of the chin, jawline, nasolabial folds and full-face volume loss. Because of its deeper injection plane and careful reconstitution, it is best suited to experienced injectors. It is for use by licensed professionals only.
Poly-L-lactic acid with CMC and mannitol, 365 mg per vial.
40 to 60 μm particles with high crystallinity.
Priced per single vial. Boxes of 15 vials are available on request.
Listed as CE certified. Not FDA-approved as a finished product.
About Proluma 365mg
Used to prompt collagen over time rather than to fill space at injection.
Listed for advanced volume loss and structural facial support, such as the chin, jawline and nasolabial folds.
The listing gives 24 months or more, with results that build over 6 to 8 weeks. This varies by patient.
The deeper plane, careful reconstitution and post-care make it best suited to mid-to-advanced level injectors.
Treatment areas and indications
Areas and concerns where PLLA collagen biostimulators are used, as listed on our previous page. Approved indications differ by market.
Deeper volume loss and loss of structural support.
Facial contouring and structural support.
Deeper folds of the lower face.
Long-term volumising plans for the whole face.
Proluma PLLA is an injectable medical product. Which indications are permitted and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training.
Proluma 365mg specification
| Product type | PLLA collagen biostimulator |
| Active ingredient | Poly-L-lactic acid (PLLA), with CMC and mannitol |
| Dose per vial | 365 mg |
| Microspheres | 40 to 60 μm, high crystallinity |
| Cannula | 26G or 25G, depending on practitioner preference |
| Box size | 15 vials per box |
| Price basis | Per single vial |
| Duration (as listed) | 24 months or more |
| Regulatory status | CE certified; not FDA-approved as a finished product |
| Manufacturer | Genèse Labs |
| SKU | 06017 |
Before you order
- Regulatory status. Proluma PLLA is listed as CE certified. It is not FDA-approved as a finished product. Confirm the status in the country where you practise.
- Priced per single vial, not per box. Boxes of 15 vials are available. Contact us for bulk box pricing.
- Every vial ships in its original packaging with the lot number and expiry date.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
Quantity discounts apply at five, ten and twenty vials.
What each component does
Poly-L-lactic acid (PLLA), 365 mg
PLLA is a biodegradable polymer. The particles are described as stimulating fibroblasts to form new collagen around them. The PLLA is gradually hydrolysed into lactic acid, which the body metabolises into carbon dioxide and water, while the newly formed collagen remains.
CMC and mannitol
Carboxymethylcellulose (CMC) helps keep the particles suspended, and mannitol acts as a stabilising component in the freeze-dried powder.
FDA GRAS status of the material
PLLA as a raw material is described as FDA GRAS (Generally Recognized As Safe). This refers to the material itself, not to FDA approval of the finished Proluma product.
Approved indications differ by country. Read the manufacturer’s instructions for use.
How it works
PLLA microspheres are described as stimulating fibroblasts to produce new collagen, which forms a matrix around the particles over weeks. The PLLA is gradually hydrolysed into lactic acid, which the body metabolises into carbon dioxide and water, while the newly formed collagen remains.
How Proluma PLLA is used
Reference information for trained practitioners. This is an advanced product. The manufacturer’s instructions for use and your training take precedence over this page, including reconstitution volumes and hydration time, needle and cannula, plane and volume per site.
Step by step
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Assess and consent
Confirm the aim is gradual structural support, not immediate volume. Review medical history, autoimmune disease, scarring tendency, medication and previous fillers. Explain the risks, including nodules.
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Reconstitute
Reconstitute the lyophilised powder exactly as stated in the instructions for use, using aseptic technique, and allow the full hydration time they give. Keep the suspension mixed before drawing it up.
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Prepare the skin
Cleanse the skin thoroughly and remove make-up.
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Inject as taught
Use the plane, technique and cannula or needle stated in the instructions for use and your training. Keep the suspension agitated during treatment. Inject slowly with low pressure.
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Do not over-correct
A biostimulator is not a filler. Do not add extra product to force an immediate change.
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Review
Assess the response over time and decide on any further treatment as a clinical decision.
Administration notes
Patients should not expect an immediate result. Redness, swelling and bruising can occur straight after treatment and may last slightly longer than with PDLLA products. The collagen-based change develops over weeks.
- Single use. Do not reuse or resterilise. Discard any remainder.
- Do not inject into infected, inflamed or broken skin.
- Know how to recognise and manage nodules and vascular events.
- Dispose of needles and cannulas into a sharps container in line with local clinical waste rules.
After treatment
- Follow the post-treatment advice in the instructions for use and your clinic’s protocol
- An ice pack can reduce swelling or bruising; keep the ice from touching the skin directly
- Avoid sun and UV exposure until initial swelling and redness subside, and use sunscreen
- Seek urgent review for severe pain, blanching, skin colour change or a lump that grows or becomes tender
Storing and handling Proluma 365mg
Store as stated in the instructions for use, away from direct light.
Use before the expiry date, and only if the packaging and vial are intact.
Single patient, single session. Do not retain or reuse any remainder.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials, syringes and needles as clinical waste in line with local requirements.
What's included with Proluma 365mg
Reconstitution fluids, syringes, needles, cannulas and anaesthetic are not supplied.
Proluma 365mg — frequently asked questions
What is Proluma PLLA?
A high-purity poly-L-lactic acid collagen biostimulator from Genèse Labs, 365 mg per vial, listed for deeper volume restoration and facial contouring.
How is Proluma PLLA different from Proluma PDLLA?
PLLA has a more crystalline structure and is listed for deeper structural volume loss. Proluma PDLLA has an amorphous, lower-crystallinity structure and is listed for earlier, smoother correction. Proluma PDLLA 200mg is listed separately.
How long do the results last?
The listing gives results that build over 6 to 8 weeks and last 24 months or more. It varies by patient and area.
Is the price per vial or per box?
Per single vial. Boxes of 15 vials are available, so contact us for bulk box pricing.
Is it FDA-approved?
No. Proluma PLLA is listed as CE certified. PLLA as a raw material is described as FDA GRAS, but that applies to the material, not to the finished product.
Who should administer it?
Mid-to-advanced level injectors, given the deeper injection plane, careful reconstitution and post-care considerations.
Who can buy and use this product?
Injectable products are for administration by licensed healthcare practitioners trained in injection technique. We supply qualified professionals and do not sell to consumers.
Customer Reviews
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This was a carefully planned purchase, and I'm pleased with the choice. Would consider it again.
I've been looking into collagen stimulators for a while. Glad I finally explored this option.
I wanted to try something beyond traditional fillers. So glad I explored this option.
Not everything needs to happen overnight. I'm very happy with my experience.
First time purchasing this brand. Really pleased with the price and overall presentation.
I wasn't looking for anything dramatic. This was just right for me.
I was prepared to wait, and I'm glad I did. Really pleased with how everything turned out.
I went into this with realistic expectations and I'm pleased with the progress.
Took my time deciding on this one. So far, I'm really pleased with my choice.
I'm glad I didn't rush to judge the results. The gradual change was exactly what I was hoping for.
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