Description

PURIHILO PN — H+L Hyaluronic Acid & Polynucleotide Skin Booster

PURIHILO PN is a hybrid skin booster from WEDERM in South Korea. It combines high- and low-molecular-weight Hyaluronic Acid with Polynucleotide (PN). Rather than adding facial volume, it targets deep hydration, tissue remodeling, and overall skin quality.

The hybrid HA complex pairs 40mg high-molecular-weight HA with 40mg low-molecular-weight HA. Together, they draw moisture into both the surface and deeper layers of skin. Medical-grade PN then supports the skin’s own repair processes. As a result, it works toward improved elasticity and reduced wrinkle severity over time.

Each box contains 1 pre-filled syringe of 2.5ml, ready to use with no reconstitution required.

Korea Filler Experts offers PURIHILO PN and ships it worldwide.

Key Benefits

• Combines high- and low-molecular-weight HA for both surface and deep hydration
• Uses certified medical-grade PN to support dermal tissue repair
• Helps remodel the extracellular matrix, supporting firmer, more resilient skin
• Associated with reduced wrinkle severity and improved facial volume loss scores in clinical evaluation
• Supports collagen formation, helping improve fine lines and skin firmness
• Comes ready to use, with no mixing or reconstitution needed

What’s Inside

Main Composition	High-molecular-weight HA (40mg), Low-molecular-weight HA (40mg), Polynucleotide (PN)
Format	Pre-filled syringe, ready to use
Packing	1 × 2.5ml syringe per box
Manufacturer	WEDERM Co., Ltd., South Korea

How PURIHILO PN Works

High-molecular-weight HA sits closer to the surface. There, it plumps and smooths the skin. Low-molecular-weight HA, on the other hand, penetrates deeper to support hydration from within. Because the two work at different depths, PURIHILO PN addresses both immediate plumpness and longer-term moisture retention in one treatment.

Medical-grade PN is built from DNA polymer, nitrogenous bases, phosphate groups, and deoxyribose. Once introduced into the dermis, it supports fibroblast activity and cell secretion. In published research, this hybrid approach has been linked to reduced wrinkle severity scores. It has also been associated with support for collagen synthesis, which contributes to firmer, more resilient skin over time.

Because the formula pairs immediate hydration with longer-term regenerative support, results tend to develop in two stages. First, patients often notice smoother, more hydrated skin shortly after treatment. Then, firmness and texture improvements build gradually as the PN component supports ongoing tissue remodeling.

Who PURIHILO PN Suits

Practitioners recommend PURIHILO PN for patients experiencing:

• Dry, dull, or dehydrated skin
• Uneven texture or roughness
• Early signs of aging or reduced elasticity
• Acne scarring or areas needing tissue repair support
• General skin revitalization needs

Treatment Areas

Face · Neck · Hands · Décolletage

Recommended Treatment Course

Practitioners typically use the full 2.5ml syringe per session. They then adjust placement based on the treatment area and skin condition. Based on published case data, a first session’s effects generally last around 6 weeks, with roughly half the benefit still present at that point.

From there, a second session 6 weeks later extends results by about 3 months. A third session, given 3 months after that, can prolong effects for up to 6 months in total.

Storage & Handling

• Store at room temperature; allow the product to reach room temperature before use if refrigerated
• Check that packaging is intact and the product is within its expiration date before opening
• Single-use only — do not reuse or resterilize
• For professional use only, by qualified and trained practitioners

Not recommended during pregnancy or breastfeeding, in patients with known hypersensitivity to any ingredient, or in areas with active skin infection or inflammation.

Frequently Asked Questions

What is PURIHILO PN?
PURIHILO PN is a hybrid skin booster from WEDERM. It combines high- and low-molecular-weight Hyaluronic Acid with Polynucleotide to support hydration, elasticity, and tissue repair.

Does PURIHILO PN add facial volume?
No. Instead, it’s designed to enhance skin quality and hydration while maintaining a natural facial appearance, unlike a dermal filler.

How many sessions are typically needed?
Many patients notice hydration and smoothness improvements after the first session. However, practitioners generally recommend a course of two to three sessions, spaced several weeks apart, for longer-lasting results.

What areas can PURIHILO PN treat?
Practitioners use it on the face, neck, hands, and body, depending on the patient’s skin needs.

How is PURIHILO PN different from Puri PDRN?
PURIHILO PN centers on a hybrid high- and low-molecular-weight HA complex plus PN. Puri PDRN, by contrast, combines PDRN with standard HA and Niacinamide for a more tone- and brightness-focused formula.

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Buy PURIHILO PN online from Korea Filler Experts, a trusted wholesale supplier of premium aesthetic injectables. We ship worldwide.