Xeomin 100UI
IncobotulinumtoxinA · 100 units per vial · lyophilised powder. Manufactured by Merz Pharma, Germany.
Original price was: $297.90.$237.90Current price is: $237.90.
- Sourced through licensed Korean distribution channels
- Temperature-controlled handling from our facility to your door
- Batch number and expiry visible before dispatch
- Practitioner support from our team
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
In accordance with applicable U.S. FDA regulations, this product is not available for purchase or shipment to U.S. addresses through this website. Customers in the United States should obtain botulinum toxin products through appropriately licensed and authorized U.S. distribution channels. A valid medical license or registration certificate is required to process any product-related claim.
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A botulinum toxin type A supplied without complexing proteins
Xeomin is the botulinum toxin type A product manufactured by Merz Pharma in Germany. Its active substance is incobotulinumtoxinA, supplied as a sterile lyophilised powder in a single 100-unit vial for reconstitution with preservative-free 0.9 % sodium chloride before use.
What distinguishes Xeomin from most toxins in this category is its formulation. Manufacturing removes the accessory complexing proteins that surround the active neurotoxin in conventional preparations, leaving the neurotoxin itself with only human albumin and sucrose as excipients. Merz markets this as a purified formulation; the clinical significance of the difference remains a matter of ongoing discussion in the literature rather than settled fact.
A practical consequence of the formulation is storage. Unopened Xeomin vials do not require refrigeration in markets where the current label permits ambient storage, which simplifies stock handling and transport compared with toxins that must be held at 2–8 °C throughout. Always work from the storage section of the prescribing information approved where you practise.
Incobotulinumtoxin A supplied without the accessory complexing proteins present in conventional toxin preparations.
Unopened vials do not require refrigeration where the approved label permits ambient storage. Check the insert for your market.
Single-use glass vial of white lyophilised powder, reconstituted with preservative-free 0.9 % sodium chloride.
Manufactured by Merz Pharma in Germany, to European pharmaceutical manufacturing standards.
Why practitioners stock this product
The manufacturing process removes the accessory proteins that accompany the neurotoxin in conventional preparations.
Where the approved label permits ambient storage of unopened vials, stock handling and transport are less demanding than for toxins requiring continuous refrigeration.
Human albumin as stabiliser and sucrose as bulking agent — a short, well-characterised excipient list.
Produced by Merz Pharma in Germany, a manufacturer with a long-established presence in this product category.
What is in each vial
| Active substance | IncobotulinumtoxinA (botulinum toxin type A, free from complexing proteins) |
| Strength | 100 Units per vial |
| Stabiliser | Human albumin, 1 mg |
| Bulking agent | Sucrose, 4.7 mg |
| Pharmaceutical form | Lyophilised powder for solution for injection |
| Appearance | White powder |
| Diluent | Preservative-free 0.9 % sodium chloride injection (not supplied) |
| Container | Single-use glass vial |
| Route | Intramuscular injection |
| Manufacturer | Merz Pharma GmbH & Co. KGaA, Germany |
| Regulatory class | Prescription-only medicine (professional use) |
Reading the carton
Before you accept a delivery, check four things:
- The lot / batch number on the carton matches the number printed on the item itself.
- The expiry date leaves you enough working life — we do not dispatch stock with under 6 months remaining unless agreed in advance.
- The seal is intact and the packaging has not been opened or disturbed.
- The parcel arrived in the condition you expect for this product, including any coolant packs still being cold.
Need the batch details first? Ask our team before you order and we will confirm the lot number and expiry date of the stock allocated to you.
Preparation and administration
Reference information for licensed practitioners. Reconstitution and administration must follow the prescribing information approved in your market and your own clinical governance procedures.
Step by step
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Inspect the vial
Check the label, lot number and expiry date. The powder should be white and the vial undamaged.
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Draw the diluent
Draw the required volume of preservative-free 0.9 % sodium chloride injection into a sterile syringe.
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Disinfect the stopper
Wipe the exposed rubber stopper with an alcohol swab and allow it to dry.
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Introduce the diluent gently
Direct the saline against the vial wall rather than onto the powder. Discard the vial if there is no vacuum drawing the diluent in.
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Mix without shaking
Rotate the vial slowly until dissolved. The solution should be clear, colourless and free of particulates.
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Record and use promptly
Note the reconstitution date and time on the vial, keep it refrigerated at 2–8 °C, and use within the period stated in your approved prescribing information.
Dilution reference
| Diluent added | Units per 0.1 mL | Total volume |
|---|---|---|
| 1.0 mL | 10.0 U | 1.0 mL |
| 2.0 mL | 5.0 U | 2.0 mL |
| 2.5 mL | 4.0 U | 2.5 mL |
| 4.0 mL | 2.5 U | 4.0 mL |
| 5.0 mL | 2.0 U | 5.0 mL |
Administration notes
- Units of botulinum toxin are product-specific. Do not convert or substitute units between different botulinum toxin brands.
- Dose per site, total dose and injection technique must follow the prescribing information approved in your market.
- A fine-gauge needle appropriate to the treatment area is normally used, and reconstituted product is drawn immediately before injection.
- Treatment intervals should not be shortened below the minimum stated in the prescribing information.
- Discard the vial if the reconstituted solution is cloudy, discoloured or contains particles.
Storage and handling
Store in the original carton. Where the approved label for your market permits ambient storage, refrigeration of unopened vials is not required. Where it does not, store at 2–8 °C. Work from the storage section of the insert supplied with your stock — this is one of the few points where Xeomin differs from most toxins, and label wording has changed between revisions.
Keep at 2–8 °C and use within the period specified in the approved prescribing information. Do not freeze reconstituted solution. Single-patient use only.
Inactivate residual product and dispose of vials, needles and syringes as clinical waste in accordance with local regulations.
Confirm the storage conditions on the carton you actually receive. Ambient storage is a property of specific approved labels, not of every Xeomin presentation in every market, and it is not an invitation to leave stock in a warm room indefinitely.
What you receive
Diluent (0.9 % sodium chloride injection), syringes and needles are not supplied with this product and must be sourced separately.
Frequently asked questions
What is Xeomin 100U?
Xeomin 100U is a botulinum toxin type A product manufactured by Merz Pharma in Germany. The active substance is incobotulinumtoxinA, supplied as a sterile lyophilised powder in a single 100-unit vial and reconstituted with preservative-free 0.9 % sodium chloride before injection by a licensed practitioner.
What does "free from complexing proteins" actually mean?
In most botulinum toxin preparations the active neurotoxin is surrounded by accessory proteins from the bacterial culture. Xeomin’s manufacturing process removes them, leaving the neurotoxin with only human albumin and sucrose as excipients. Merz presents this as a purified formulation. Whether the difference changes clinical outcomes is still discussed in the literature rather than settled, so it is best described as a formulation characteristic rather than a proven advantage.
Does Xeomin need refrigeration?
This is where Xeomin differs from most toxins. Under the current labelling in several markets, unopened vials do not require refrigeration and may be stored at or below 25 °C. Older label revisions permitted room temperature, refrigerated or frozen storage. Because the wording has changed over time and varies by market, follow the storage section of the insert supplied with your stock rather than a general rule.
How is it reconstituted?
With preservative-free 0.9 % sodium chloride injection. Dilution volume is chosen by the practitioner: 2.5 mL into a 100-unit vial gives 4 units per 0.1 mL, which is a commonly used concentration. The reference table in the How to Use section lists other volumes. Always follow the reconstitution instructions in the prescribing information approved for your market.
Can I substitute Xeomin units for another brand's units?
No. Units of botulinum toxin are specific to each product and are not interchangeable between brands. Dosing must be taken from the prescribing information for the product in your hand.
Who is allowed to buy this product?
Botulinum toxin is a prescription-only medicine. Purchase and use are restricted to licensed healthcare professionals qualified to prescribe or administer injectable prescription medicines in their jurisdiction, with appropriate training in the relevant anatomy and injection technique. We do not sell to consumers.
Can I get the batch number and expiry before ordering?
Yes. Ask our team and we will confirm the lot number and expiry date of the stock allocated to your order before it is dispatched. We do not ship product with less than six months of remaining shelf life unless you have specifically agreed to it.
Customer Reviews
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Sometimes it's worth paying a little extra for a brand you already know.
I liked the subtle effect and professional experience. The result was natural, which was more important to me than a dramatic change.
Very natural effect. Exactly what I wanted.
Very natural result. Exactly what I wanted.
I liked the subtle result and the fact that my appearance still looked like myself afterward.
I liked the subtle effect and the professional experience. The result looked natural, which was my main priority.
I liked the subtle effect and professional experience. The result was natural, which was more important to me than a dramatic change.
I chose this because I wanted a more natural appearance. The overall result was subtle and matched my expectations.
I liked that the effect was subtle. My goal was improvement without looking different, and that is what I achieved.
I liked the subtle effect and the fact that my face still looked like me afterwards. The whole process was simple and professional.
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