NCTF 135 HA
Non-cross-linked hyaluronic acid with vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals and antioxidants · 3 mL vials · Fillmed
Original price was: $550.00.$530.00Current price is: $530.00.
- NCTF 135 HA is a polyrevitalizing mesotherapy solution from Fillmed (formerly Filorga), combining non-crosslinked hyaluronic acid with 55 active ingredients — vitamins, amino acids, coenzymes, and antioxidants — for comprehensive skin revitalization.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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NCTF 135 HA: a polyrevitalising skin booster
NCTF 135 HA is a skin revitalisation solution from Fillmed. It combines non-cross-linked, non-animal hyaluronic acid at 5 mg/mL with the NCTF complex — a blend of vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals and antioxidants — and is placed in the dermis by multipuncture.
It sits in a different corner of the skin-booster market from Profhilo and from polynucleotide products. Instead of one active, it delivers hyaluronic acid together with a mixed nutrient formula, and it is used to improve the hydration, radiance and fine texture of ageing or tired skin. It is not designed to add volume.
Fillmed states that NCTF 135 HA is CE marked and MDR certified (since February 2025). Fillmed’s practitioner brochure sets out a three-step approach: a superficial peel, biorevitalisation by intradermal multipuncture, then skincare.
Non-cross-linked hyaluronic acid at 5 mg/mL, rich in water, for skin that looks dehydrated and tired.
Vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals and antioxidants blended with the HA.
A revitalising solution placed in the dermis. It is not intended to add volume or contour.
A multicentre randomised study of the NCTF 135 HA protocol on face, neck and décolleté has been published.
Why practitioners stock NCTF 135 HA
Fillmed publishes a practitioner brochure and has supported a randomised multicentre study, so the course structure is documented and easy to explain to patients.
In the published protocol two 3 mL vials treated the full face and one vial treated the neck or décolleté, which makes treatment planning and ordering straightforward.
Commonly used on its own for dull, dehydrated skin or added to a plan alongside peels, toxin and fillers.
Fillmed states the product is CE marked and MDR certified. You can check this against the manufacturer’s documentation before you buy.
Treatment areas and indications
Areas and concerns where NCTF 135 HA is used in practice. All are skin-quality indications.
Skin that looks tired and lacks radiance, where the aim is better hydration and a fresher appearance.
Superficial wrinkles and fine surface texture. A published randomised study assessed superficial wrinkles and skin quality after this protocol.
Included in the published protocol, using one 3 mL vial for the area.
Used on its own or alongside peels, toxin and filler as part of a skin-quality plan.
NCTF 135 HA is an injectable medical product. Which indications are permitted and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition, and nothing here replaces manufacturer training or the instructions for use.
NCTF 135 HA specification
| Product | NCTF 135 HA — polyrevitalising skin booster |
| Hyaluronic acid | Non-cross-linked, non-animal, 5 mg/mL |
| NCTF complex | Vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals, antioxidants |
| Presentation | 3 mL vial |
| Typical pack | 5 × 3 mL |
| Technique | Intradermal multipuncture |
| Course in published study | 3 sessions at day 0, 21 and 42 |
| Volume per area (study) | 2 vials full face; 1 vial neck or décolleté |
| Manufacturer | Fillmed, France |
| SKU | 08062 |
Before you order
- Check the lot number and expiry on the carton against the vial.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
- Store as stated on the carton. Do not freeze, and protect from light.
- Regulatory status varies by country. Fillmed states the product is CE marked. Confirm that it is lawful to import and use where you practise.
Tiered pricing applies from 5 units. A full-face course uses two vials per session, so most clinics order in multiples.
What each component does
What is in it
Fillmed describes NCTF 135 HA as a non-cross-linked sodium hyaluronate solution combined with a proprietary cocktail of vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals and antioxidants.
The manufacturer does not publish the concentration of each component. Distributor listings quote different totals — different pages give 53, 55 and 59 ingredients — so we do not state a number. For a definitive ingredient list, refer to the carton and the instructions for use.
Non-cross-linked hyaluronic acid
Because the hyaluronic acid is not chemically cross-linked, it is a fluid that disperses in the dermis rather than a gel that holds shape. That is why NCTF 135 HA is used to improve skin quality and hydration and why it should not be offered as a way to add volume.
How it differs from other skin boosters
Profhilo combines high- and low-molecular-weight hyaluronic acid in hybrid complexes and is placed at a small number of points. Polynucleotide products such as Rejuran use a purified DNA polymer. NCTF 135 HA uses hyaluronic acid with a nutrient cocktail and is delivered by multipuncture across the treatment area. They are different tools, and the right one depends on the patient’s skin and your protocol.
How NCTF 135 HA is used
Reference information for trained practitioners. The manufacturer’s instructions for use and Fillmed training take precedence over this page, including for dose per point and point spacing.
Step by step
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Assess and consent
Confirm the aim is hydration and skin quality. Review medical history, medication and any history of reactions to hyaluronic acid. Explain the course structure and that results build over the course.
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Prepare the skin
Remove make-up and cleanse thoroughly. Fillmed’s protocol begins with a superficial peel before injection; follow the manufacturer’s guidance if you include this step.
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Anaesthesia
Topical anaesthetic is commonly used because multipuncture covers a wide area. Check whether the formulation you are using contains any anaesthetic.
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Draw up and prepare
Prepare the solution aseptically from the 3 mL vial using the needle and syringe set specified in the instructions for use.
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Inject by multipuncture
Place the solution intradermally across the treatment area in small, evenly spaced aliquots. Take the dose per point and the spacing from the instructions for use.
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Plan the course
In the published randomised study, sessions were given at day 0, day 21 and day 42. Fillmed’s brochure notes that two further sessions can be recommended if necessary.
Administration notes
Multipuncture means many small marks. Expect small papules and pinpoint redness at the injection points. These usually settle within a short time, but patients should plan around social events for the first day or two.
Describe the result honestly. The aim is better-hydrated, fresher-looking skin with improved fine texture. It does not lift, tighten or replace volume.
- Single use. One vial, one patient, one session. Discard any remainder.
- Do not inject into infected, inflamed or broken skin.
- There is no clinical tolerance data for injecting into an area already treated with a permanent filler, so avoid it.
- Dispose of needles into a sharps container in line with local clinical waste rules.
After treatment
- Redness, small papules, swelling and bruising at the injection points are common
- Patients taking anticoagulants or antiplatelet drugs such as aspirin may bruise more and bleed slightly at the points
- Avoid make-up for about 12 hours
- Avoid prolonged sun and UV exposure, extreme cold, saunas and steam baths for at least 48 hours
- Seek review for severe pain, spreading redness or an unexpected firm lump
Storing and handling NCTF 135 HA
Store as stated on the carton and in the manufacturer’s instructions for use, protected from light. Do not freeze.
Check the vial, seal and expiry. Do not use a vial that is damaged, discoloured or contains visible particles.
Single patient, single session. Do not store or reuse an opened vial.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials, syringes and needles as clinical waste in line with local requirements.
What's included with NCTF 135 HA
Fillmed also offers packs with an injecting kit. Check the carton for exactly what is included with the pack you receive.
NCTF 135 HA — frequently asked questions
What is NCTF 135 HA?
A polyrevitalising skin booster from Fillmed. It combines non-cross-linked, non-animal hyaluronic acid at 5 mg/mL with the NCTF complex of vitamins, amino acids, co-enzymes, nucleic acid derivatives, minerals and antioxidants, and is delivered into the dermis by multipuncture.
How many ingredients does NCTF 135 HA contain?
Distributor listings give different totals — 53, 55 and 59 all appear — and the manufacturer does not publish the concentration of each component. We therefore do not quote a number. The carton and instructions for use are the authority.
Does NCTF 135 HA add volume?
No. The hyaluronic acid is not cross-linked and the product is not intended to add volume or contour. It is used to improve hydration and skin quality.
How many sessions are needed?
In a published randomised multicentre study, patients received three sessions at day 0, 21 and 42. Fillmed’s practitioner brochure notes that two additional sessions can be recommended if necessary. Your protocol should follow the manufacturer’s instructions for use.
How much product is used?
In the published study, two 3 mL vials treated the full face and one 3 mL vial treated the neck or décolleté. Dose per injection point and point spacing are set out in the instructions for use.
Is it CE marked?
Fillmed states that NCTF 135 HA is CE marked and MDR certified since February 2025. Regulatory status differs between countries, so confirm it is lawful to import and use where you practise.
How does it compare with Profhilo or Rejuran?
They are different tools. Profhilo uses hybrid high- and low-molecular-weight hyaluronic acid placed at a small number of points. Rejuran uses a purified polynucleotide. NCTF 135 HA uses hyaluronic acid with a nutrient complex, delivered by multipuncture. Choose according to the patient’s skin and your protocol.
What are the common side effects?
Redness, small papules, swelling and bruising at the injection points. Patients on anticoagulants or antiplatelet drugs may bruise and bleed slightly more. Serious reactions are uncommon but the instructions for use list the full warnings.
Can it be used on the neck and décolleté?
Yes. The published protocol included the neck and décolleté, using one 3 mL vial for that area.
Who can buy and use this product?
Injectable products are for administration by licensed healthcare practitioners. We supply qualified professionals and do not sell to consumers.

