Dermaheal SB
Three biomimetic peptides with arbutin, licorice extract and a stable vitamin C derivative · 5 mL × 10 vials · Caregen, South Korea. Marketed for uneven skin tone.
Original price was: $89.90.$69.90Current price is: $69.90.
- Dermaheal SB is a mesotherapy solution from Caregen combining three biomimetic peptides with arbutin, licorice extract and a vitamin C derivative, marketed for dull skin and uneven tone.
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
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Dermaheal SB: a tone-focused mesotherapy solution
Dermaheal SB is a mesotherapy solution from Caregen, the company behind Dermaheal SR and Revofil. It combines three biomimetic peptides with three better-known actives for skin tone — arbutin, licorice root extract and 3-O-ethyl ascorbic acid, a stable vitamin C derivative.
It is marketed for dull skin and uneven tone, including sun-related discolouration. Caregen’s description is that the combination works on several steps of pigment formation at once. That is the manufacturer’s account of the formula, and we are not aware of independent peer-reviewed clinical trials for this product.
Pigmentation is a diagnostic question before it is a treatment question. Melasma, post-inflammatory marks, sun damage and suspicious lesions need different handling, so patients should be assessed before any course starts.
Oligopeptide-34, Pentapeptide-13 and Oligopeptide-50 combined with arbutin, licorice extract and 3-O-ethyl ascorbic acid.
Caregen describes the combination as acting on more than one step of pigment formation. This is the manufacturer's description.
The vitamin C derivative is a stable form of vitamin C, included for its antioxidant and tone-evening role.
Not every pigment concern suits a skin-level treatment. Diagnosis comes first.
Why practitioners stock Dermaheal SB
Clinics already using Dermaheal SR or HSR can add a formula aimed at tone and dullness rather than general rejuvenation.
Arbutin, licorice extract and a vitamin C derivative are widely known in tone-evening skincare, which simplifies the consultation.
Ten 5 mL vials give enough product for several patients or for a full course for one.
Commonly combined with strict sun protection, home care and, where appropriate, other in-clinic treatments.
Treatment areas and indications
Concerns where the manufacturer positions this product. All are cosmetic skin-tone concerns.
Skin that has lost radiance, where the aim is a fresher, more even look.
Patchy tone and surface discolouration, after the pigment type has been assessed.
Superficial marks associated with sun exposure, alongside strict sun protection.
Dermaheal SB is a mesotherapy product. Which indications are permitted, how mesotherapy solutions are classified and what training is required are set by the regulatory framework where you practise. Korea Filler Experts supplies the product. Nothing here is a recommendation to treat any medical condition.
What is inside Dermaheal SB
| Peptides | Oligopeptide-34 (CG-TGP2), Pentapeptide-13 (CG-ASP), Oligopeptide-50 |
| Other actives | Arbutin, licorice root extract, 3-O-ethyl ascorbic acid |
| Presentation | 5 mL vials |
| Pack | 10 vials |
| Delivery | Mesotherapy or microneedling |
| Treatment area | Face |
| Manufacturer | Caregen Co, Ltd, South Korea |
| SKU | 08009 |
Before you order
- Check the lot number and expiry on the carton against the vials.
- We do not dispatch stock with under 6 months of shelf life remaining unless agreed in advance.
- Store as stated on the carton, away from direct light.
- Regulatory classification of mesotherapy solutions differs between markets. Confirm that the product is lawful to import and use by injection where you practise.
Tiered pricing applies from 5 units for clinics that stock several boxes.
What each component does
The actives and their described roles
- Oligopeptide-34 (CG-TGP2) — described by distributors as reducing melanin synthesis by limiting the transfer of melanin to skin cells.
- Pentapeptide-13 (CG-ASP) and Oligopeptide-50 — supporting biomimetic peptides in the Caregen complex.
- Arbutin — a plant-derived compound widely used in skincare and described as inhibiting tyrosinase, the enzyme involved in pigment formation.
- Licorice root extract — a botanical used in tone-evening and soothing formulas.
- 3-O-ethyl ascorbic acid — a stable derivative of vitamin C with antioxidant activity.
These descriptions come from Caregen and distributors. They describe intended functions, not demonstrated clinical results.
When a pigment concern is not a good fit
- Melasma — chronic, hormonally influenced and prone to relapse. It needs a dedicated plan and realistic expectations.
- New, changing or irregular lesions — need medical assessment, not a mesotherapy course.
- Deeper dermal pigment — less likely to respond to surface-acting actives.
How Dermaheal SB is used
Reference information for trained practitioners. The manufacturer’s instructions for use and training take precedence over this page, including the session schedule, which varies between distributor descriptions.
Step by step
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Assess the pigmentation
Identify the type and depth of pigment. Examine for any lesion that needs medical review. Ask about melasma, hormonal factors, sun exposure and previous reactions.
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Consent and expectations
Explain that results are gradual and vary, and that daily sun protection is part of the plan, not an extra.
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Prepare the skin
Remove make-up and cleanse thoroughly. Apply topical anaesthetic if required.
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Draw up and deliver
Draw up one 5 mL vial aseptically. Deliver by mesotherapy or microneedling according to your training and the instructions for use.
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Plan the course
Follow the manufacturer’s schedule. Review the response between sessions and stop if irritation or post-inflammatory darkening develops.
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Aftercare
Strict daily sun protection, no make-up for the period set by your protocol, and avoidance of saunas and strenuous exercise for 48 hours.
Administration notes
Sun protection decides the outcome. Needling or injecting an area and then allowing sun exposure can darken it. A daily broad-spectrum sunscreen is part of the treatment plan.
Watch deeper skin tones. Any procedure that inflames the skin can cause post-inflammatory hyperpigmentation, which is more likely in patients with deeper skin tones. Consider this before choosing the delivery method.
- Single use. One vial, one patient. Discard any remainder.
- Do not treat over active infection, inflamed or broken skin.
- Dispose of needles into a sharps container in line with local clinical waste rules.
After treatment
- Redness, small marks and mild swelling are common and usually settle within days
- Use broad-spectrum sun protection every day
- Avoid saunas, steam rooms and heavy exercise for 48 hours
- Seek review for severe pain, spreading redness or new darkening of the treated skin
Storing and handling Dermaheal SB
Store as stated on the carton and in the manufacturer’s insert, away from direct light.
Check the vial, seal and expiry. Do not use a vial that is damaged, discoloured or contains visible particles.
Single patient, single session. Do not retain or reuse an opened vial.
Do not use if the packaging is damaged or the expiry date has passed. Dispose of used vials, syringes and needles as clinical waste in line with local requirements.
What's included with Dermaheal SB
Needles, syringes and topical anaesthetic are not supplied.
Dermaheal SB — frequently asked questions
What is Dermaheal SB?
A mesotherapy solution from Caregen combining three biomimetic peptides with arbutin, licorice root extract and 3-O-ethyl ascorbic acid. It is marketed for dull skin and uneven tone.
What are the active ingredients?
Oligopeptide-34 (CG-TGP2), Pentapeptide-13 (CG-ASP), Oligopeptide-50, arbutin, licorice root extract and 3-O-ethyl ascorbic acid, a stable vitamin C derivative. The full list is on the carton.
How does it work?
Caregen and distributors describe the combination as acting on more than one step of pigment formation — arbutin as a tyrosinase inhibitor, Oligopeptide-34 as limiting melanin transfer, and the vitamin C derivative as an antioxidant. These are the manufacturer’s descriptions. We are not aware of independent clinical trials for this product.
Can it treat melasma?
We do not market it for melasma. Melasma is chronic, hormonally influenced and prone to relapse, and it needs a dedicated plan and realistic expectations.
How many sessions are needed?
Distributor schedules differ, so follow the manufacturer’s instructions for use and review the patient’s response between sessions.
Is sun protection necessary?
Yes. Daily broad-spectrum sun protection is part of any plan for uneven tone, and sun exposure after needling can worsen pigmentation.
How is it different from Dermaheal SR?
SR is Caregen’s general-purpose peptide formula for skin quality. SB is aimed at tone and dullness, and adds arbutin, licorice extract and a vitamin C derivative.
What size is the pack?
Ten 5 mL vials.
Who can buy and use this product?
Mesotherapy products are for administration by licensed healthcare practitioners. We supply qualified professionals and do not sell to consumers.
Customer Reviews
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The product itself is excellent and delivers very good results. However, the expiration date of the package I received was less than six months away, which is disappointing.
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