Description

• Revofil — Biomimetic Peptide Hyaluronic Acid Filler Series

  Revofil is a hyaluronic acid (HA) dermal filler series from Caregen Co., Ltd., a South Korean biopharmaceutical company known for its peptide research. The series spans three variants — Fine, Plus, and Ultra. Each combines cross-linked HA with Caregen’s biomimetic peptide technology.

  What sets Revofil apart is Oligopeptide-72, a peptide that binds to both cross-linked and non-cross-linked HA. This peptide specifically inhibits the enzyme hyaluronidase, which naturally breaks HA down in the body. Because of this, Revofil resists degradation more effectively than many standard HA fillers.

  At a Glance

  Technology	Biomimetic peptide (Oligopeptide-72) + cross-linked HA
  Structure	Hybrid biphasic and monophasic characteristics
  Duration	10–12 months
  Regulatory Status	Not yet FDA-approved
  Manufacturer	Caregen Co., Ltd., South Korea

  Main Benefits

  • Peptide-enhanced hyaluronidase resistance: Oligopeptide-72 slows the natural breakdown of HA, extending duration
  • Hybrid gel structure: combines biphasic and monophasic qualities for both viscosity and elasticity
  • Immediate, long-lasting results: visible effects right away, with duration extending to 10–12 months
  • Natural, firming effect: supports a lifted, rejuvenated appearance without an overfilled look
  • Three depth tiers: covers fine lines through deep structural volumizing

  Choosing the Right Variant

  Variant	Injection Depth	Best For
  Revofil Fine	Superficial dermis	Fine lines, superficial wrinkles, and caved scars — forehead, nose bridge, smile lines, around the eyes
  Revofil Plus	Middle and deep dermis	Deep wrinkles and facial volume — lips, cheeks, nasolabial folds, marionette lines
  Revofil Ultra	Deep tissue	Facial contour redefinition and intense volumizing — forehead, nose bridge, jawline

  Caregen also produces Revofil AquaShine, a separate biorevitalizing skin booster distinct from the core Fine, Plus, and Ultra fillers.

  What’s Inside

  Active Ingredients	Cross-linked Hyaluronic Acid, biomimetic peptide (Oligopeptide-72)
  Other Components	Endogenous hyaluronic acid, elastin, collagen, and other extracellular matrix (ECM) components
  Manufacturer	Caregen Co., Ltd., South Korea

  How Revofil Works

  Biomimetic peptides in Revofil form ionic bonds with both cross-linked and non-cross-linked HA in the gel. This strengthens the gel’s overall structure, improving its elasticity and stability once injected.

  The same peptide, Oligopeptide-72, also inhibits hyaluronidase, the enzyme responsible for breaking HA down naturally in the body. This slows the gel’s degradation. As a result, Revofil maintains its volume and shape over a longer period than many comparable fillers, while also supporting the skin’s own collagen and elastin production.

  Who Revofil Suits

  Practitioners recommend Revofil for patients interested in:

  • Softening fine lines and superficial wrinkles
  • Correcting nasolabial folds, marionette lines, and lip volume
  • Deep facial contouring and structural volumizing
  • Patients seeking a firming, lifting effect alongside wrinkle correction

  Treatment Areas

  Forehead · Nose bridge · Smile lines and periorbital area · Lips · Cheeks · Nasolabial folds · Marionette lines · Jawline

  Storage & Handling

  • Store at room temperature
  • Use immediately upon opening
  • Single-use only — do not reuse or resterilize
  • For professional use only, by qualified and trained practitioners

  Not recommended during pregnancy or breastfeeding, in patients with known hypersensitivity to HA, or in areas with active skin infection or inflammation.

  Frequently Asked Questions

  What is Revofil?
  Revofil is a hyaluronic acid dermal filler series from Caregen, built on biomimetic peptide technology and available in three variants: Fine, Plus, and Ultra.

  How do I choose between Fine, Plus, and Ultra?
  Revofil Fine suits fine lines and superficial wrinkles. Revofil Plus suits deeper wrinkles and facial volume. Revofil Ultra suits intense volumizing and facial contour redefinition.

  What makes Revofil different from standard HA fillers?
  Its biomimetic peptide, Oligopeptide-72, inhibits the enzyme that naturally breaks HA down in the body, helping the gel last longer than many standard fillers.

  Is Revofil FDA-approved?
  Not yet. Revofil is currently pending FDA approval, so practitioners in regions requiring FDA clearance should verify local regulations before use.

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