Description

• Hyafilia — V-Phasic Hyaluronic Acid Filler Series

  Hyafilia is a hyaluronic acid (HA) dermal filler series from CHA Meditech Co., Ltd., a South Korean bioaesthetics company founded in 2013 as part of the CHA Bio Group. The series uses V-Phasic Technology. This structure combines qualities of both monophasic and biphasic fillers in one gel.

  The formula blends 85% stabilized HA with 15% native, non-stabilized HA. This hybrid structure gives Hyafilia both the plasticity of biphasic gels and the smooth consistency of monophasic gels. The series spans three variants for different correction depths.

  At a Glance

  HA Structure	85% stabilized + 15% native HA
  Technology	V-Phasic (hybrid mono/biphasic)
  Duration	6–14 months, depending on variant
  Shelf Life	36 months from manufacturing date
  Manufacturer	CHA Meditech Co., Ltd., South Korea

  Main Benefits

  • Hybrid gel structure: combines biphasic plasticity with monophasic smoothness
  • Non-animal HA: bio-fermentation origin means no skin test is required before treatment
  • Body-matched osmolarity: close to natural interstitial fluid, supporting better tolerance and less inflammation
  • Clinically validated: trials have demonstrated non-inferiority to established HA fillers in wrinkle severity scoring

  Choosing the Right Variant

  Variant	Particle Size	Best For	Injection Depth
  Hyafilia Petit	Smallest	Very fine, superficial lines	Upper dermis
  Hyafilia Classic	Medium	Moderate wrinkles	Middle dermis
  Hyafilia Grand	Largest	Deep folds and wrinkles	Deep dermis to subcutaneous layer

  CHA Meditech also produces a related line, Hyafilia ME:DAM, which uses similar V-Phasic technology with lidocaine included.

  What’s Inside

  Active Ingredient	Cross-linked, non-animal Hyaluronic Acid
  Structure	85% stabilized HA, 15% native HA
  Other Ingredients	Sterile, pyrogen-free water for injection
  Manufacturer	CHA Meditech Co., Ltd., South Korea

  How Hyafilia Works

  Standard monophasic fillers offer smooth consistency but can lack structural firmness. Biphasic fillers offer firmness but can feel less uniform. V-Phasic Technology aims to combine both. It uses a cross-linking process with a high degree of cross-linking, over 6 mol%, which supports a longer duration before the gel breaks down.

  Because the manufacturing process purifies out residual BDDE, the cross-linking agent used during production, the finished gel carries minimal leftover BDDE. Combined with an osmolarity close to the body’s own interstitial fluid, this supports a more comfortable treatment with less redness and swelling than some comparable fillers.

  Who Hyafilia Suits

  Practitioners recommend Hyafilia for patients interested in:

  • Correcting fine, superficial lines
  • Moderate wrinkle and fold correction
  • Deep fold correction and facial volumizing
  • Post-acne scar improvement
  • Patients seeking a filler that doesn’t require a skin test beforehand

  Treatment Areas

  Nasolabial folds · Fine facial lines · Moderate-to-deep wrinkles · Post-acne scars · Facial volumizing zones

  Administration

  Practitioners typically inject Hyafilia using microdroplet, serial puncture, or linear threading techniques, depending on the treatment area and variant. The manufacturing process uses a double aseptic technique, so the finished product carries a reduced risk of post-treatment infection. Even so, practitioners should still follow standard aseptic protocol during injection.

  Storage & Handling

  • Store at room temperature, in original sterile packaging
  • Use immediately upon opening
  • Single-use only — do not reuse or resterilize
  • For professional use only, by qualified and trained practitioners

  Not recommended during pregnancy or breastfeeding, in patients with known hypersensitivity to HA, or in areas with active skin infection or inflammation.

  Frequently Asked Questions

  What is Hyafilia?
  Hyafilia is a hyaluronic acid dermal filler series from CHA Meditech, built on V-Phasic technology. It combines monophasic and biphasic filler qualities and comes in three variants: Petit, Classic, and Grand.

  How do I choose between Petit, Classic, and Grand?
  Hyafilia Petit suits very fine, superficial lines. Hyafilia Classic suits moderate wrinkles. Hyafilia Grand suits deep folds and facial volumizing.

  Does Hyafilia contain lidocaine?
  The base Hyafilia line generally doesn’t include lidocaine, giving practitioners flexibility to manage pain independently. However, the related Hyafilia ME:DAM line does include lidocaine.

  How long do results last?
  Results generally last 6 to 14 months, depending on the variant and treatment area.

  Does Hyafilia require a skin test before treatment?
  No. Because Hyafilia is made from non-animal HA through bio-fermentation, it doesn’t require a skin test before the procedure.

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