Botaone 100UI
Clostridium botulinum toxin type A (CBFC-26 strain) · 100 units · albumin-free lyophilised powder, single-dose vial. Manufactured by Genetox Co, Ltd, South Korea.
$55.90
Botaone 100UI is an albumin-free botulinum toxin type A from Genetox, built on their proprietary CBFC-26 strain and tested using ethical in vitro methods instead of animal-based testing. Results generally last at least 6 months.
- Sourced through licensed Korean distribution channels
- Temperature-controlled handling from our facility to your door
- Batch number and expiry visible before dispatch
- Practitioner support from our team
Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.
In accordance with applicable U.S. FDA regulations, this product is not available for purchase or shipment to U.S. addresses through this website. Customers in the United States should obtain botulinum toxin products through appropriately licensed and authorized U.S. distribution channels. A valid medical license or registration certificate is required to process any product-related claim.
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An albumin-free botulinum toxin type A from Genetox
Botaone 100UI is a botulinum toxin type A product from Genetox Co, Ltd. in South Korea. Two things make its specification unusual in this category: the formulation is albumin-free, and Genetox uses in vitro potency testing rather than the animal-based assay still standard across most of the industry.
Albumin-free matters for a specific group of patients. Human serum albumin is the stabiliser in almost every toxin product, and it is a human blood derivative — a point some patients raise on religious, ethical or personal grounds. Having an albumin-free option lets you answer that question with a product rather than a conversation.
Each vial holds 100 units of lyophilised powder with a 36-month shelf life, which suits clinics that hold stock. The specification table below lists the full composition, storage and registration details.
No human serum albumin, which answers the blood-derivative question directly for patients who raise it.
Genetox uses a cell-based assay rather than the animal-based LD50 method still standard in this industry.
Longer than the 24 months common in this class, which matters when you hold stock rather than order per patient.
Supplied as a white lyophilised powder, so concentration is set at the bench to suit the treatment area.
Why practitioners choose Botaone 100UI
The small but real group of patients who decline human blood derivatives can be offered a product rather than turned away. Coretox and Innotox are the other albumin-free options we carry.
Potency has traditionally been measured by a mouse LD50 assay. In vitro cell-based testing replaces it — a point some clinics raise with patients as a matter of principle.
A 36-month shelf life gives more room to buy in quantity without racing the expiry date.
Positioned as a Korean-manufactured alternative at a lower price point than the established Western brands.
Aesthetic & therapeutic applications
Areas commonly treated with botulinum toxin type A. Given this product’s registration status, every application below is one you must confirm is permitted where you practise before offering it.
Vertical lines between the brows produced by corrugator and procerus activity — the area most commonly treated with botulinum toxin type A, and usually the first in a new patient.
Lines at the outer eye produced by orbicularis oculi activity. A lower-concentration dilution is often preferred here for finer control of a thin, superficial muscle.
Fine lines around the mouth, treated with very small doses. A conservative area: the perioral muscles are involved in speech and eating, so over-treatment is functionally noticeable rather than just cosmetic.
Not an anatomical indication, but the clearest reason to stock this product. An albumin-free option lets a patient who would otherwise decline treatment proceed.
Botulinum toxin products are prescription-only medicines. Genetox describes Botaone’s regulatory registrations as in progress; any decision to purchase or administer it rests with the treating practitioner under their own professional judgement and local regulatory framework. Korea Filler Experts supplies the product; nothing here should be read as a recommendation to treat any medical condition.
What is inside Botaone 100UI
| Active substance | Clostridium botulinum toxin type A |
| Strain | CBFC-26, Genetox proprietary strain |
| Strength | 100 Units per vial |
| Human serum albumin | None — albumin-free formulation |
| Pharmaceutical form | Lyophilised white powder for solution for injection |
| Appearance | White dry powder in a clear glass vial |
| Potency testing | In vitro (cell-based) assay |
| Shelf life | 36 months from manufacture |
| Diluent | Preservative-free 0.9% sodium chloride injection (not supplied) |
| Container | Single-use glass vial |
| Route | Intramuscular injection |
| Manufacturer | Genetox Co, Ltd, South Korea |
| Regulatory status | Manufacturer states MFDS and FDA registration in progress — verify locally |
Reading the carton
Before you accept a delivery, check four things:
- The unit count matches what you ordered.
- The lot / batch number on the carton matches the number printed on the vial.
- The expiry date leaves you enough working life — we do not dispatch stock with under 6 months remaining unless agreed in advance.
- The carton arrived cold, with the coolant pack still chilled.
Before your first order: confirm that a product in this regulatory position may be purchased and administered where you practise. That check is yours to make, and it is the one we would most want you to make.
What each component does
- Botulinum toxin type A — the active substance. It temporarily reduces the release of acetylcholine at the neuromuscular junction, lowering activity in the injected muscle.
- No human serum albumin — the defining feature of this formulation. Albumin is the standard stabiliser elsewhere in the category, used to stop the toxin protein adsorbing to the glass. Albumin-free products achieve that stability through an alternative excipient system.
Why albumin-free is worth having on the shelf
Human serum albumin is derived from donated human plasma. The processing it undergoes makes transmission of infection a theoretical rather than a practical concern, and albumin-containing toxins have an extensive safety record.
But some patients decline products of human origin — on religious grounds, as vegans or on broader ethical grounds, or simply as a personal preference. That is a question you cannot answer by explaining risk statistics, because it is not a risk question. An albumin-free product on the shelf lets the patient proceed. Botaone, Coretox and Innotox all serve that role in our range.
On in vitro potency testing: botulinum toxin potency has historically been defined by a mouse LD50 assay, which requires animal testing for every batch released. Cell-based in vitro alternatives have been validated and adopted by several manufacturers. Genetox states it uses one. This is a manufacturing-ethics point rather than a clinical one — the resulting product behaves the same way.
How to prepare and use Botaone 100UI
Reference information for licensed practitioners. Reconstitution and administration must follow the manufacturer’s package insert and any prescribing information applicable in your market.
Step by step
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Inspect the vial
Check the label, unit count, lot number and expiry date, and confirm the seal is intact. The contents should be a white dry powder.
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Choose your concentration
Decide the diluent volume before you start, based on the treatment areas planned for the session. The table below sets out common dilutions.
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Introduce the diluent slowly
Insert the needle at an angle and let the vacuum draw the preservative-free 0.9% saline in. Direct the stream against the vial wall rather than onto the powder.
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Mix gently
Rotate the vial slowly to dissolve the contents. Do not shake vigorously. The solution should be clear, colourless and free of particulates.
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Record and use promptly
Note the reconstitution date and time on the vial, store at 2–8 °C, and use within the period stated in the manufacturer’s insert.
Dilution reference
| Diluent added | Units per 0.1 mL | Total volume |
|---|---|---|
| 1.0 mL | 10.0 U | 1.0 mL |
| 2.0 mL | 5.0 U | 2.0 mL |
| 2.5 mL | 4.0 U | 2.5 mL |
| 4.0 mL | 2.5 U | 4.0 mL |
| 5.0 mL | 2.0 U | 5.0 mL |
Administration notes
Materials needed: preservative-free 0.9% sterile saline, a sterile syringe with a fine-gauge needle, gloves and alcohol swabs. None of these are supplied with the vial.
- Units of botulinum toxin are product-specific. Do not convert or substitute units between brands — and be particularly careful here, because albumin-free products are sometimes assumed to be interchangeable with each other. They are not.
- Dose per site, total dose and injection technique must follow the manufacturer’s insert.
- Draw reconstituted product immediately before injection.
- Single-patient use. Discard any remainder rather than carrying it to the next appointment.
- Treatment intervals should not be shortened below the minimum stated in the insert.
After treatment
- Avoid rubbing or massaging the treated area for at least 24 hours
- Stay upright and avoid lying down for 4 to 6 hours
- Avoid strenuous exercise for 24 to 48 hours
- Avoid saunas, hot tubs and excessive sun exposure for at least 24 hours
- Mild redness, swelling or bruising can occur and usually settles within a few days
Storing and handling Botaone 100UI
Store refrigerated at 2–8 °C in the original carton, protected from light. Do not freeze. The 36-month shelf life runs from manufacture — work to the expiry date printed on the carton rather than counting from delivery.
Keep at 2–8 °C and use within the period stated in the manufacturer’s insert. Single-patient use only.
Transfer stock into a monitored medical refrigerator on arrival and keep a temperature log. If a shipment arrives warm, photograph the packaging and contact us before putting it into clinical service.
Do not use the vial if the contents are discoloured, if the reconstituted solution is cloudy or contains particles, if the expiry date has passed, or if the cold chain is known to have been broken. Dispose of unused product and used vials as clinical waste in line with local requirements.
What's included with Botaone 100UI
Diluent (0.9% sodium chloride injection), syringes and needles are not supplied with this product and must be sourced separately.
Botaone 100UI — frequently asked questions
What is Botaone 100UI?
Botaone 100UI is an albumin-free botulinum toxin type A product manufactured by Genetox Co, Ltd. in South Korea, built on the company’s CBFC-26 strain. It is supplied as a lyophilised white powder in a single 100-unit vial and reconstituted with preservative-free 0.9% sodium chloride before injection by a licensed practitioner.
Is Botaone approved by the MFDS or the FDA?
No. Genetox describes registration with both agencies as in progress rather than complete, and we are not aware of that having changed.
Please confirm what you are permitted to purchase and administer in your own jurisdiction before ordering.
What does albumin-free mean, and who is it for?
Almost every botulinum toxin product uses human serum albumin — a plasma-derived protein — as its stabiliser. Botaone does not.
That matters for patients who decline products of human origin, whether on religious grounds, as vegans, or as a personal preference. It is not primarily a safety argument: albumin-containing toxins have a long and good safety record. It is about being able to treat a patient who would otherwise decline.
What are the other albumin-free options you carry?
Coretox (Medytox) and Innotox (Medytox) are both albumin-free, and both hold Korean MFDS approval, which Botaone does not. If the albumin question is what brought you to this page, those are worth comparing against it.
What is in vitro potency testing?
Botulinum toxin potency has traditionally been measured by a mouse LD50 assay, which requires animal testing for each batch. Validated cell-based in vitro alternatives now exist and several manufacturers have adopted them. Genetox states it uses one.
This is a manufacturing-ethics point rather than a clinical one — it does not change how the product behaves in the patient.
How long does the effect last?
Published evidence for botulinum toxin type A in aesthetic use generally supports a review interval of around three to four months, varying by treatment area, dose and individual patient.
We have removed longer figures that appeared in earlier versions of this listing, because they were not supported by the published evidence for this product class.
Can I substitute Botaone units for another brand's units?
No. Units of botulinum toxin are specific to each product and are not interchangeable between brands — including between one albumin-free product and another. Dosing must be taken from the insert for the product in your hand.
Will it give a frozen look?
That depends on dose and placement, not on the brand. Any toxin A product can produce an over-treated result if too many units are placed in the wrong muscle, and any can give a natural one in trained hands. Treat claims to the contrary — ours or anyone’s — with suspicion.
What shelf life will my stock have?
We do not dispatch stock with less than six months of remaining shelf life unless you have specifically agreed to it. The long total shelf life on this line usually means stock arrives with well over that. If you need a particular expiry window, tell us before you order.
What happens if my shipment arrives warm?
Do not use it. Photograph the outer box, the insulated liner, the coolant packs and the vial carton, and contact us the same day with your order number. We will review the cold-chain evidence and arrange a replacement where the failure occurred in transit.
Who is allowed to buy this product?
Botulinum toxin is a prescription-only medicine. Purchase and use are restricted to licensed healthcare professionals qualified to prescribe or administer injectable prescription medicines in their jurisdiction, with appropriate training in the relevant anatomy and injection technique. We do not sell to consumers.
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