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Nabota 200UI

Clostridium botulinum toxin type A · 200 units · lyophilised powder, single-dose vial. Manufactured by Daewoong Pharmaceutical, South Korea.

200 UPer vial
Type AToxin serotype
2–8 °CStorage
36 moShelf life
SKU: 03015
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$92.90
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Volume pricing
1 – 4 $92.90 base price
5 – 9 $91.51 1.5 % off
10 – 19 $90.58 2.5 % off
20+ $89.65 3.5 % off
  • Nabota 200UI delivers double the toxin content of the standard vial from Daewoong Pharmaceutical, suiting larger or multi-zone treatment sessions. It shares the same FDA/EMA/Health Canada approval and Hi-Pure Technology as the 100UI version.
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1 - 4 — $92.90
5 - 9 1.5% $91.51
10 - 19 2.5% $90.58
20+ 3.5% $89.65
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Professional use only. This product is intended for administration by licensed healthcare practitioners trained in the relevant anatomy and injection technique. By ordering you confirm you are authorised to purchase and handle products of this class in your jurisdiction. Availability and permitted use vary by country — please verify local regulations before ordering.

Important Information for U.S. Customers:

In accordance with applicable U.S. FDA regulations, this product is not available for purchase or shipment to U.S. addresses through this website. Customers in the United States should obtain botulinum toxin products through appropriately licensed and authorized U.S. distribution channels. A valid medical license or registration certificate is required to process any product-related claim.

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Product overview

The 200-unit Nabota vial, for higher-volume treatment sessions

Nabota 200UI is the larger vial in Daewoong Pharmaceutical’s botulinum toxin type A range. The formulation is identical to the 100 U and 150 U presentations — what changes is the fill, and therefore how many vials you open in a session.

This size suits practitioners combining facial treatment with larger muscle groups such as masseter or platysma, or running consecutive appointments where a smaller vial would be exhausted early. Because reconstituted product is single-patient use, the right vial size is the one that matches a single session rather than a week of bookings.

The active substance — prabotulinumtoxinA — was the first Asian-manufactured botulinum toxin to gain United States FDA approval, marketed there as Jeuveau and in Europe and Canada as Nuceiva. Those are separate registrations: a Korean-market Nabota carton is not the FDA-approved US article, and we do not represent it as one.

Fewer vials per session

Double the units of the 100 U presentation, for lists combining facial work with larger muscle groups.

Published Phase III evidence

The active substance was studied in two identical randomised placebo-controlled trials in glabellar lines.

Practitioner-set dilution

Reconstitution volume is chosen by the injector — a 200 U vial takes twice the saline of a 100 U vial for the same concentration.

Conventional formulation

Botulinum toxin type A with human serum albumin as stabiliser and sodium chloride for tonicity.

Day 0 Treatment administered
Days 1–3 Onset commonly reported
Day 30 Phase III efficacy endpoint
3–4 months Typical review interval
Retreatment As clinically indicated
Key features

Why practitioners choose Nabota 200UI

Sized for higher-volume sessions

Masseter, platysma or consecutive appointments run through a 100 U vial quickly. This size reduces how many you open and how many reconstitutions you perform.

A published Phase III record

Two identical randomised, placebo-controlled trials of the active substance in glabellar lines reported day-30 responder rates of 67.5% and 70.4% against placebo.

Approved internationally under partner brands

The same active substance holds FDA approval as Jeuveau and European and Canadian approval as Nuceiva.

Interchangeable within the range

100 U, 150 U and 200 U share one formulation, so vial size can change without changing product.

Indications & Treatment Areas

Aesthetic & therapeutic applications

The approved indication for the active substance is set out first. The remaining areas are commonly treated in practice — and are where a 200-unit vial is typically used — but approval status differs between markets.

Lower face and jawline

Masseter and platysma treatment for muscle contouring, which is the main reason practitioners choose the larger vial. Approval status varies widely by country and this is frequently a practitioner-led application rather than a labelled indication.

Glabellar lines (frown lines)

Temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adults. This is the indication under which the active substance holds international approval.

Lateral canthal lines (crow's feet)

Lines at the outer eye produced by orbicularis oculi activity. Widely treated in aesthetic practice, though not covered by the US approval of the partner brand.

Forehead lines

Horizontal forehead lines from frontalis activity. When the main work of a session is lower face, forehead treatment is usually a small share of the total dose. A practitioner decision within local regulations.

A note on scope

Botulinum toxin products are prescription-only medicines. Any use outside the indications approved in your jurisdiction is a clinical decision made by the treating practitioner under their own professional judgement and local regulatory framework. Korea Filler Experts supplies the product; nothing here should be read as a recommendation to treat any medical condition.

Composition

What is inside Nabota 200UI

Active substance Clostridium botulinum toxin type A (haemagglutinin complex)
Strength 200 Units per vial
Stabiliser Human serum albumin
Tonicity agent Sodium chloride
Pharmaceutical form Lyophilised powder for solution for injection
Appearance White to off-white cake or powder
Diluent Preservative-free 0.9% sodium chloride injection (not supplied)
Container Type I glass vial, rubber stopper, aluminium flip-off cap
Route Intramuscular injection
Shelf life Up to 36 months from manufacture
Manufacturer Daewoong Pharmaceutical Co, Ltd, Republic of Korea
Regulatory class Prescription-only medicine (professional use)

Reading the carton

Before you accept a delivery, check four things:

  • The lot / batch number on the carton matches the number printed on the vial label.
  • The expiry date leaves you enough working life — we do not dispatch stock with under 6 months remaining unless agreed in advance.
  • The flip-off cap is intact and the vial seal has not been disturbed.
  • The carton arrived cold, with the coolant pack still chilled.

Vial looks empty? The contents are freeze-dried under vacuum, so the powder forms a thin film that is hard to see against the glass. This is expected and is not a sign of a short fill.

What each component does

  • Botulinum toxin type A — the active substance. It temporarily reduces the release of acetylcholine at the neuromuscular junction, lowering activity in the injected muscle.
  • Human serum albumin — stabilises the toxin protein through freeze-drying, storage and reconstitution.
  • Sodium chloride — brings the reconstituted solution to a tonicity suitable for injection.
How to use

How to prepare and use Nabota 200UI

Reference information for licensed practitioners. Diluent volumes for a 200-unit vial are double those of a 100-unit vial to reach the same concentration. Reconstitution and administration must follow the prescribing information approved in your market.

Step by step

  1. Bring the vial to working condition

    Take the vial from refrigerated storage and inspect the label, lot number and expiry date. Confirm the flip-off cap is intact.

  2. Calculate the diluent volume

    Work from the 200 U column. A 200 U vial needs 5.0 mL to reach 4 units per 0.1 mL — double what a 100 U vial would take.

  3. Disinfect the stopper

    Remove the flip-off cap and wipe the exposed rubber stopper with an alcohol swab. Allow it to dry.

  4. Introduce the diluent slowly

    Insert the needle at an angle and let the vacuum draw the saline in. Direct the stream against the vial wall rather than onto the powder.

  5. Mix gently

    Rotate the vial slowly to dissolve the cake. Do not shake vigorously — agitation can denature the protein. The solution should be clear, colourless and free of particulates.

  6. Record and use promptly

    Note the reconstitution date and time on the vial, store at 2–8 °C, and use within the period stated in your approved prescribing information.

Dilution reference

Diluent added Units per 0.1 mL Total volume
2.0 mL 10.0 U 2.0 mL
2.5 mL 8.0 U 2.5 mL
4.0 mL 5.0 U 4.0 mL
5.0 mL 4.0 U 5.0 mL
8.0 mL 2.5 U 8.0 mL
10.0 mL 2.0 U 10.0 mL

Administration notes

Check the vial size before you dilute. The volumes above are double those for a 100 U vial. Adding 2.5 mL to a 200 U vial gives 8 units per 0.1 mL, not 4 — a common slip when switching vial size mid-list.

Materials needed: preservative-free 0.9% sterile saline, a sterile syringe with a fine-gauge needle, gloves and alcohol swabs. None of these are supplied with the vial.

  • Units of botulinum toxin are product-specific. Do not convert or substitute units between brands.
  • Dose per site, total dose and injection technique must follow the prescribing information approved in your market.
  • Draw reconstituted product immediately before injection.
  • Treatment intervals should not be shortened below the minimum stated in the prescribing information.

After treatment

  • Avoid rubbing or massaging the treated area for at least 24 hours
  • Stay upright and avoid lying down for 4 to 6 hours
  • Avoid strenuous exercise for 24 to 48 hours
  • Avoid saunas, hot tubs and excessive sun exposure for at least 24 hours
  • Mild redness, swelling or bruising can occur and usually settles within a few days
Storage & handling

Storing and handling Nabota 200UI

Unopened vial

Store refrigerated at 2–8 °C in the original carton, protected from light. Do not freeze. Shelf life is up to 36 months from manufacture — always work to the printed expiry date.

After reconstitution

Keep at 2–8 °C and use within the period specified in your approved prescribing information. Single-patient use only — a 200 U vial is not pooled across patients.

Cold chain on arrival

Transfer stock into a monitored medical refrigerator on arrival and keep a temperature log. If a shipment arrives warm, photograph the packaging and contact us before putting it into clinical service.

Handling and shipping note

Do not use the vial if the powder is discoloured, if the reconstituted solution is cloudy or contains particles, if the expiry date has passed, or if the cold chain is known to have been broken. Dispose of unused product and used vials as clinical waste in line with local requirements.

In the box

What's included with Nabota 200UI

1 × Nabota 200 U vial Lyophilised powder, sealed
Original Daewoong carton With lot number and expiry date
Manufacturer package insert Korean-market labelling
Insulated cold-chain packaging Coolant packs and liner
Batch and expiry confirmation Available before dispatch on request
Tracked shipping Tracking number issued on dispatch

Diluent (0.9% sodium chloride injection), syringes and needles are not supplied with this product and must be sourced separately.

FAQ

Nabota 200UI — frequently asked questions

What is Nabota 200UI?

Nabota 200UI is a botulinum toxin type A product manufactured by Daewoong Pharmaceutical in South Korea. It is supplied as a sterile freeze-dried powder in a single 200-unit vial and reconstituted with preservative-free 0.9% sodium chloride before injection by a licensed practitioner.

How does it differ from the 100 U and 150 U vials?

Only in how many units are in the vial. The formulation and excipients are identical. The practical difference is dilution: to reach 4 units per 0.1 mL you add 5.0 mL to a 200 U vial, 3.75 mL to a 150 U vial and 2.5 mL to a 100 U vial.

Is Nabota the same as Jeuveau?

The active substance is the same — prabotulinumtoxinA — and it received United States FDA approval in February 2019, marketed there as Jeuveau. In Europe and Canada the same substance is approved as Nuceiva.

Those are separate registrations. A Korean-market Nabota carton is not the FDA-approved, US-labelled article, and we do not represent it as such.

Which vial size should I order?

Size the vial to a single session rather than to a week of bookings, because reconstituted product is single-patient use. The 100 U vial suits face-focused lists; 150 U and 200 U reduce how many you open when treating larger muscle groups or running consecutive appointments.

Why does the vial look empty?

The contents are freeze-dried under vacuum, so the active substance forms a very thin, almost transparent film in the vial. This is normal for lyophilised toxins and is not a sign of a short fill.

Can I substitute Nabota units for another brand's units?

No. Units of botulinum toxin are specific to each product and are not interchangeable between brands. Dosing must be taken from the prescribing information for the product in your hand.

What shelf life will my stock have?

We do not dispatch stock with less than six months of remaining shelf life unless you have specifically agreed to it. If you need a particular expiry window, tell us before you order and we will allocate accordingly.

What happens if my shipment arrives warm?

Do not use it. Photograph the outer box, the insulated liner, the coolant packs and the vial carton, and contact us the same day with your order number. We will review the cold-chain evidence and arrange a replacement where the failure occurred in transit.

Who is allowed to buy this product?

Botulinum toxin is a prescription-only medicine. Purchase and use are restricted to licensed healthcare professionals qualified to prescribe or administer injectable prescription medicines in their jurisdiction, with appropriate training in the relevant anatomy and injection technique. We do not sell to consumers.