Description

Rejuran HB — PDRN & Hyaluronic Acid Hydro Booster with Lidocaine

Rejuran HB is a PDRN skin booster from PharmaResearch, part of the Rejuran family alongside Healer, I, and S. Unlike the other variants, HB combines PDRN with hyaluronic acid (HA) and lidocaine in one formula. This pairs regeneration with immediate hydration and a more comfortable injection.

Because lidocaine is built directly into the formula, patients often describe Rejuran HB as the most comfortable option in the line, which is part of why practitioners frequently recommend it to first-time patients.

At a Glance

Active Ingredients	Polydeoxyribonucleotide (PDRN) + Hyaluronic Acid (HA)
Anesthetic	Lidocaine
Packing	1cc vial
Duration	6–12 months per treatment course
Manufacturer	PharmaResearch, South Korea

Main Benefits

• Combines regeneration with hydration: PDRN and HA work together for both structural repair and immediate plumping
• Built-in lidocaine: significantly reduces pain during injection compared to other Rejuran formulas
• Ideal for first-time patients: the more comfortable option for those new to PDRN treatment
• Supports fibroblast activity: the PN and HA combination is associated with increased fibroblast proliferation compared to either ingredient alone
• Suits dry, dehydrated skin: delivers deep hydration alongside regenerative benefits

What’s Inside

Active Ingredients	Polydeoxyribonucleotide (PDRN) and Hyaluronic Acid (HA)
Anesthetic	Lidocaine
Format	Lower-viscosity solution, 1cc vial
Manufacturer	PharmaResearch, South Korea

Rejuran products carry CE certification. They are not currently approved by the US FDA for aesthetic use.

How Rejuran HB Works

Once injected, PDRN activates adenosine A2A receptors on skin cells, prompting fibroblasts to produce new collagen and elastin. Alongside this, the formula’s hyaluronic acid draws in and holds moisture. This delivers an immediate plumping and hydrating effect that PDRN alone doesn’t provide as quickly.

According to the manufacturer, combining these two ingredients supports greater fibroblast activity than either would achieve alone. Meanwhile, the built-in lidocaine numbs the treatment area during injection, making the overall experience noticeably more comfortable than higher-viscosity Rejuran formulas.

Who Rejuran HB Suits

Practitioners recommend Rejuran HB for patients interested in:

• Dry, dehydrated, or dull skin
• Combined hydration and regeneration in one treatment
• Patients new to PDRN treatment who want a more comfortable first experience
• General skin barrier support and revitalization

Treatment Areas

Full face · Neck · General skin revitalization zones

Administration

A licensed practitioner administers Rejuran HB via intradermal injection. Because the formula includes lidocaine, patients typically experience less discomfort than with other Rejuran variants. A typical treatment course includes 3 to 4 sessions, spaced several weeks apart.

Precautions

• For use by licensed medical professionals only
• Not recommended during pregnancy or breastfeeding
• Avoid in patients with known hypersensitivity to PDRN, HA, lidocaine, or fish-derived products
• Avoid in areas with active skin infection or inflammation

Storage & Handling

• Store at room temperature, away from direct light
• Single-use only — do not reuse or resterilize
• For professional use only, by qualified and trained practitioners

Frequently Asked Questions

What is Rejuran HB?
Rejuran HB is a PDRN and hyaluronic acid skin booster from PharmaResearch, with built-in lidocaine for a more comfortable injection alongside its regenerative and hydrating benefits.

Why is Rejuran HB recommended for first-time patients?
Because it contains lidocaine, the injection is noticeably more comfortable than higher-viscosity Rejuran formulas, making it a common starting point for patients new to PDRN treatment.

How is Rejuran HB different from Rejuran Healer?
Rejuran Healer uses pure PDRN at medium viscosity, while Rejuran HB combines PDRN with hyaluronic acid and lidocaine for added hydration and comfort.

How many sessions are needed?
Most practitioners recommend a course of 3 to 4 sessions, spaced several weeks apart, for best results.

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