Description

Rejuran Tone-Up Booster — Two-Part PDRN Brightening Solution

Rejuran Tone-Up Booster is a two-part topical mesotherapy solution from PharmaResearch, designed to brighten skin tone while supporting collagen production. Rejuran’s standalone injectable formulas work differently. Unlike those, Tone-Up Booster is applied topically after microneedling (MTS) or fractional laser treatment.

The system combines two vials: a PDRN-based toning solution and a brightening solution containing Vitamin C, glutathione, and tranexamic acid. Practitioners mix the two together and apply immediately after treatment. Together, they address both dullness and deeper skin quality concerns.

At a Glance

Vial 1	Hydrolyzed DNA (c-PDRN), sodium hyaluronate, panthenol
Vial 2	Ascorbic acid, glutathione, tranexamic acid
Application	Topical, following MTS or fractional laser treatment
Manufacturer	PharmaResearch, South Korea

Main Benefits

• Two-part active system: combines PDRN regeneration with a dedicated brightening solution
• Targets pigmentation and dullness: Vitamin C, glutathione, and tranexamic acid work together to even skin tone
• Supports collagen production: c-PDRN helps firm and regenerate skin alongside its brightening effect
• Deep hydration: sodium hyaluronate and panthenol support moisture alongside the active ingredients
• Post-procedure friendly: designed for use immediately after MTS or fractional laser treatment

What’s Inside

Vial 1 (Toning Solution)	Purified water, hydrolyzed DNA (c-PDRN), sodium chloride, sodium hyaluronate, panthenol
Vial 2 (Brightening Solution)	Purified water, sucrose, ascorbic acid, glutathione, tranexamic acid, sodium hydroxide, 1,2-hexanediol
Packing	6 vials total (3 of each type)
Manufacturer	PharmaResearch, South Korea

In the United States, Rejuran products are marketed as topical cosmetic items rather than injectable drug products, in line with current FDA regulations.

How Rejuran Tone-Up Booster Works

The toning solution’s c-PDRN component supports collagen production and skin regeneration, while sodium hyaluronate and panthenol provide hydration. Once mixed with the brightening solution, ascorbic acid, glutathione, and tranexamic acid work together to target pigmentation and even out skin tone.

The formula is applied after microneedling or fractional laser treatment. Because of this, the micro-channels created by these procedures allow the solution to penetrate more effectively than it would on unbroken skin. This combination approach is what allows Tone-Up Booster to address both brightness and deeper skin quality concerns in one session.

Who Rejuran Tone-Up Booster Suits

Practitioners recommend Rejuran Tone-Up Booster for patients interested in:

• Dull, uneven skin tone
• Pigmentation concerns alongside general skin quality
• Post-procedure care following microneedling or fractional laser treatment
• Combined brightening and collagen support in one topical treatment

Treatment Areas

Face — applied following in-office microneedling or fractional laser procedures

Administration

A practitioner mixes Vial 1 and Vial 2 together immediately before use, then applies the combined solution to the skin right after MTS or fractional laser treatment. The mixed solution should be used immediately and not stored for later application.

Precautions

• For use by licensed medical or aesthetic professionals only
• Discontinue use if redness, swelling, or itching develops, particularly with sun exposure
• Avoid in patients with known hypersensitivity to any formula component
• Avoid in areas with active skin infection or inflammation

Storage & Handling

• Store at room temperature, between 1°C and 30°C
• Keep away from direct sunlight
• Use within 1 day of opening

Frequently Asked Questions

What is Rejuran Tone-Up Booster?
Rejuran Tone-Up Booster is a two-part topical solution from PharmaResearch, combining PDRN-based toning with a Vitamin C and glutathione brightening formula, applied after microneedling or laser treatment.

Is Tone-Up Booster injected like other Rejuran products?
No. Rejuran Healer, I, S, and HB are all injected directly. Unlike those, Tone-Up Booster is a topical formula applied to the skin after MTS or fractional laser treatment.

How do I use the two vials?
Mix Vial 1 and Vial 2 together immediately before use, then apply the combined solution right after an MTS or fractional laser procedure.

What does Tone-Up Booster help with?
It targets dullness and uneven pigmentation while supporting collagen production and hydration, making it a common post-procedure treatment.

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